In recent years, visible light-induced transition metal catalysis has emerged as a new
paradigm in organic photocatalysis, which has led to the discovery of unprecedented …

Transition-metal-catalyzed C–H activation has developed a contemporary approach to the
omnipresent area of retrosynthetic disconnection. Scientific researchers have been tempted …

Radical intermediates in organic chemistry lack a full octet of electrons and, thus, are
commonly said to be electron deficient. By denotation, such a statement is technically …

The polarity of a radical intermediate profoundly impacts its reactivity and selectivity. To
quantify this influence and predict its effects, the electrophilicity/nucleophilicity of> 500 …

Selective functionalization of ubiquitous unactivated C–H bonds is a continuous quest for
synthetic organic chemists. In addition to transition metal catalysis, which typically operates …

The synthetic utility of aryl radicals has been established in the last century, however, their
broad applications were hampered by ineffective generation methods. It was in the last …

Despite the widespread applications of α-hydroxyalkyl cyclic amines, direct and diverse
access to such a class of unique vicinal amino alcohols still remains, to date, a challenge …

Despite the success of Sonogashira coupling for the synthesis of arylalkynes and
conjugated enynes, the engagement of unactivated alkyl halides in such reactions remains …

The development of a mild and general method for C (sp3)− H functionalization of cyclic
amines has been an ongoing challenge. In this work, we describe the copper‐catalyzed …

Diradical generation followed by radical–radical cross-coupling is a powerful synthetic tool,
but its detailed mechanism has yet to be established. Herein, we proposed and confirmed a …