The autosomal dominantly inherited disorder von Hippel–Lindau disease (VHL) is caused
by germline mutations in the VHL tumour suppressor gene (TSG). VHL mutations …

Pheochromocytomas (PCCs) and paragangliomas (PGLs) are catecholamine-secreting
tumors of neural crest origin. Once collectively known as the '10% tumor', based on the …

This volume covers tumors of the pituary, the thyroid and parathyroid, the adrenal gland, the
endocrine pancreas, and inherited tumor syndromes. Each entity is extensively discussed …

Abstract von Hippel–Lindau (VHL) disease is a hereditary cancer syndrome that is
characterized by the development of multiple vascular tumors and is caused by inactivation …

Mutation of the VHL tumor suppressor is associated with the inherited von Hippel–Lindau
(VHL) cancer syndrome and the majority of kidney cancers. VHL binds the ElonginC …

Germ-line mutations of the von Hippel-Lindau tumor suppressor gene (VHL) predispose
individuals to a variety of human tumors, and somatic mutations of this gene have been …

Object. The goals of this study were to define the natural history and growth pattern of
hemangioblastomas of the central nervous system (CNS) that are associated with von …

Succinate dehydrogenase B (SDHB) and D (SDHD) subunit gene mutations predispose to
adrenal and extraadrenal pheochromocytomas, head and neck paragangliomas (HNPGL) …

Mutations in the von Hippel-Lindau (VHL) gene are responsible for VHL disease, congenital
polycythemia, and are found in many sporadic tumor types as well. Reports of VHL …

Abstract von Hippel-Lindau disease, which is characterized by an increased risk of
hemangioblastomas, clear cell renal carcinomas, and pheochromocytomas, is caused by …