Akt is a serine/threonine kinase and it participates in the key role of the PI3K signaling
pathway. The Akt can be activated by a wide range of growth signals and the biochemical …

Breast cancer (BC) is the most common cancer in women and poses a serious threat to their
health. Despite familiarity with factors affecting its etiology, initiation, progression, treatment …

Although the first discovery of a non-coding RNA (ncRNA) dates back to 1958, only in recent
years has the complexity of the transcriptome started to be elucidated. However, its …

Cardiac remodeling, which is characterized by mechanical and electrical remodeling, is a
significant pathophysiological process involved in almost all forms of heart diseases …

Human cancers are characterized by a number of hallmarks, including sustained
proliferative signaling, evasion of growth suppressors, activated invasion and metastasis …

MicroRNAs (miRs) are small single-stranded RNA molecules, which function as key
negative regulators of post-transcriptional modulation in almost all biological processes …

The highly conserved RAS-mitogen activated protein kinase (MAPK) signaling pathway is
involved in a wide range of cellular processes including differentiation, proliferation, and …

MicroRNAs are small non-coding RNAs that participate in different biological processes,
providing subtle combinational regulation of cellular pathways, often by regulating …

Breast cancer is one of the most lethal malignancies in women in the world. Various factors
are involved in the development and promotion of the malignancy; most of them involve …

Activation of the PI3K/AKT pathway, a common mechanism in all subtypes of endometrial
cancers (endometrioid and non-endometrioid tumors), has important roles in contributing to …