Analyzing the microbiome of diverse species and environments using next-generation
sequencing techniques has significantly enhanced our understanding on metabolic …

A planetary-scale understanding of the ocean ecosystem, particularly in light of climate
change, is crucial. Here, we review the work of Tara Oceans, an international …

Metagenomic assembly enables new organism discovery from microbial communities, but it
can only capture few abundant organisms from most metagenomes. Here we present …

Insulin resistance is the primary pathophysiology underlying metabolic syndrome and type 2
diabetes,. Previous metagenomic studies have described the characteristics of gut …

Antibiotics are used to fight pathogens but also target commensal bacteria, disturbing the
composition of gut microbiota and causing dysbiosis and disease. Despite this well-known …

Background Recent evidence suggests a role for the microbiome in pancreatic ductal
adenocarcinoma (PDAC) aetiology and progression. Objective To explore the faecal and …

The gut microbiome is shaped through infancy and impacts the maturation of the immune
system, thus protecting against chronic disease later in life. Phages, or viruses that infect …

Association studies have linked microbiome alterations with many human diseases.
However, they have not always reported consistent results, thereby necessitating cross …

Natural microbial communities are phylogenetically and metabolically diverse. In addition to
underexplored organismal groups, this diversity encompasses a rich discovery potential for …

Microbial genes encode the majority of the functional repertoire of life on earth. However,
despite increasing efforts in metagenomic sequencing of various habitats,–, little is known …