Abstract Apelin and Elabela (Ela) are peptides encoded by APLN and APELA, respectively,
which act on their receptor APJ and play crucial roles in the body. Recent research has …

The apelinergic system, which includes the apelin receptor (APJ) as well as its two specific
ligands, namely apelin and ELABELA (ELA/APELA/Toddler), have been the subject of many …

Background Preeclampsia is a placentally induced syndrome with diverse clinical
presentation that currently has no cure. Oxidative stress is a potent inducer of placental …

Cardiovascular disease is the leading cause of death worldwide. Its prevalence is rising due
to ageing populations and the increasing incidence of diseases such as chronic kidney …

Apelin is an endogenous ligand for the G protein-coupled receptor APJ and has multiple
biological activities in human tissues and organs, including the heart, blood vessels …

Introduction: Fetal growth disturbances place fetuses at increased risk for perinatal morbidity
and mortality. As yet, little is known about the basic pathogenetic mechanisms underlying …

The aim of this study was to investigate the possible protective effects of apelin, which is
known to have antioxidant and anti-inflammatory effects, on changes in neurogenesis in …

The apelinergic system is a highly conserved pleiotropic system. It comprises the apelin
receptor apelin peptide jejunum (APJ) and its two peptide ligands, Elabela/Toddler (ELA) …

Aims: To investigate maternal circulating apelin levels in pregnancies with and without
preeclampsia. Design and Method: Systematic review and meta-analysis of observational …

The apelinergic system, which includes the apelin receptor (APJ) as well as its two specific
ligands, namely apelin and ELABELA (ELA/APELA/Toddler), have been the subject of many …