Mitochondrial dysfunction and heart disease: critical appraisal of an overlooked association

G Bisaccia, F Ricci, S Gallina, A Di Baldassarre… - International Journal of …, 2021 - mdpi.com
The myocardium is among the most energy-consuming tissues in the body, burning from 6 to
30 kg of ATP per day within the mitochondria, the so-called powerhouse of the …

Human-induced pluripotent stem cell technology and cardiomyocyte generation: progress and clinical applications

A Di Baldassarre, E Cimetta, S Bollini, G Gaggi… - Cells, 2018 - mdpi.com
Human-induced pluripotent stem cells (hiPSCs) are reprogrammed cells that have hallmarks
similar to embryonic stem cells including the capacity of self-renewal and differentiation into …

Mesenchymal stem cells for cardiac regeneration: from differentiation to cell delivery

S Gupta, A Sharma, RS Verma - Stem Cell Reviews and Reports, 2021 - Springer
Mesenchymal stem cells (MSCs) are so far the most widely researched stem cells in clinics
and used as an experimental cellular therapy module, particularly in cardiac regeneration …

The effects of combined exposure to bisphenols and perfluoroalkyls on human perinatal stem cells and the potential Implications for health outcomes

A Di Credico, G Gaggi, I Bucci, B Ghinassi… - International Journal of …, 2023 - mdpi.com
The present study investigates the impact of two endocrine disruptors, namely Bisphenols
(BPs) and Perfluoroalkyls (PFs), on human stem cells. These chemicals leach from plastic …

Human mesenchymal amniotic fluid stem cells reveal an unexpected neuronal potential differentiating into functional spinal motor neurons

G Gaggi, A Di Credico, S Guarnieri… - Frontiers in Cell and …, 2022 - frontiersin.org
Human amniotic fluids stem cells (hAFSCs) can be easily isolated from the amniotic fluid
during routinely scheduled amniocentesis. Unlike hiPSCs or hESC, they are neither …

Spare parts from discarded materials: Fetal annexes in regenerative medicine

G Gaggi, P Izzicupo, A Di Credico, S Sancilio… - International Journal of …, 2019 - mdpi.com
One of the main aims in regenerative medicine is to find stem cells that are easy to obtain
and are safe and efficient in either an autologous or allogenic host when transplanted. This …

Fibroblast activation protein-α in tumor cells promotes colorectal cancer angiogenesis via the Akt and ERK signaling pathways

F Cao, S Wang, H Wang… - Molecular medicine …, 2018 - spandidos-publications.com
Fibroblast activation protein-α (FAP-α) is a cell surface serine protease of the post-prolyl
peptidase family, and stromal FAP-α expression may serve important functions in tumor …

Effect of physical exercise on the release of microparticles with angiogenic potential

A Di Credico, P Izzicupo, G Gaggi, A Di Baldassarre… - Applied Sciences, 2020 - mdpi.com
Cellular communication has a fundamental role in both human physiological and
pathological states and various mechanisms are involved in the crosstalk between organs …

Relationship of Cx43 regulation of vascular permeability to osteopontin-tight junction protein pathway after sepsis in rats

J Zhang, G Yang, Y Zhu, X Peng… - American Journal of …, 2018 - journals.physiology.org
Our previous study demonstrated that connexin (Cx) 43 participated in the regulation of
vascular permeability in severe sepsis. Osteopontin (OPN) has been demonstrated to …

The influence of maturity status on anthropometric profile and body composition of youth goalkeepers

A Di Credico, G Gaggi, B Ghinassi… - International Journal of …, 2020 - mdpi.com
The anthropometric profile assessment is an important aspect to consider during the growth
stages of youth sport practitioners due to its usefulness in controlling maturity status and …