Triple‑negative breast cancer (TNBC) accounts for 10‑15% of all breast cancer cases.
TNBCs lack estrogen and progesterone receptors and express low levels of HER2, and …

Androgens are essential sex steroid hormones for both sexes. Testosterone (T) is the
predominant androgen in males, while in adult females, T concentrations are about 15-fold …

Owing to the development of multiple novel therapies, there has been major progress in the
treatment of advanced prostate cancer over the last two decades; however, the disease …

Despite significant progress in breast cancer (BC) therapy, it is globally the most commonly
diagnosed cancer and leads to the death of over 650,000 women annually. Androgen …

Statistics provided by GLOBOCAN list gastric cancer as the sixth most common, with a
mortality ranking of third highest for the year 2020. In China, a herb called Rabdosia …

Androgens in women, as well as in men, are intrinsic to maintenance of (i) reproductive
competency,(ii) cardiac health,(iii) appropriate bone remodeling and mass retention,(iii) …

In recent years, with the successful development of proteolysis-targeting chimeric molecules
(PROTACs), the potential of heterobifunctional molecules to contribute to reenvisioning drug …

Cancer is the world's second leading cause of mortality and one of the major public health
problems. Cancer incidence and mortality rates remain high despite the great …

Chemotherapy resistance is identified as an obstacle for breast cancer (BC) therapy, and,
besides, increasing evidence indicates that long-noncoding RNAs (lncRNAs) participate in …

Hanahan and Weinberg introduced the “hallmarks of cancer” and typified essential
biological abilities acquired by human cancer. Since then, a growing understanding of …