Mechanistic pathways of sex differences in cardiovascular disease
V Regitz-Zagrosek, G Kararigas - Physiological reviews, 2017 - journals.physiology.org
Major differences between men and women exist in epidemiology, manifestation,
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …
Testosterone and obesity
DM Kelly, TH Jones - Obesity Reviews, 2015 - Wiley Online Library
Testosterone is a key hormone in the pathology of metabolic diseases such as obesity. Low
testosterone levels are associated with increased fat mass (particularly central adiposity) …
testosterone levels are associated with increased fat mass (particularly central adiposity) …
Muscle wasting and cachexia in heart failure: mechanisms and therapies
S Von Haehling, N Ebner, MR Dos Santos… - Nature Reviews …, 2017 - nature.com
Body wasting is a serious complication that affects a large proportion of patients with heart
failure. Muscle wasting, also known as sarcopenia, is the loss of muscle mass and strength …
failure. Muscle wasting, also known as sarcopenia, is the loss of muscle mass and strength …
Testosterone and cardiovascular disease
RA Kloner, C Carson, A Dobs, S Kopecky… - Journal of the American …, 2016 - jacc.org
Testosterone (T) is the principal male sex hormone. As men age, T levels typically fall.
Symptoms of low T include decreased libido, vasomotor instability, and decreased bone …
Symptoms of low T include decreased libido, vasomotor instability, and decreased bone …
Adverse events associated with testosterone administration
S Basaria, AD Coviello, TG Travison… - … England Journal of …, 2010 - Mass Medical Soc
Background Testosterone supplementation has been shown to increase muscle mass and
strength in healthy older men. The safety and efficacy of testosterone treatment in older men …
strength in healthy older men. The safety and efficacy of testosterone treatment in older men …
Testosterone therapy and cardiovascular events among men: a systematic review and meta-analysis of placebo-controlled randomized trials
Background Testosterone therapy is increasingly promoted. No randomized placebo-
controlled trial has been implemented to assess the effect of testosterone therapy on …
controlled trial has been implemented to assess the effect of testosterone therapy on …
Testosterone replacement therapy and cardiovascular risk
T Gagliano-Jucá, S Basaria - Nature Reviews Cardiology, 2019 - nature.com
Testosterone is the main male sex hormone and is essential for the maintenance of male
secondary sexual characteristics and fertility. Androgen deficiency in young men owing to …
secondary sexual characteristics and fertility. Androgen deficiency in young men owing to …
Testosterone deficiency is associated with increased risk of mortality and testosterone replacement improves survival in men with type 2 diabetes
V Muraleedharan, H Marsh, D Kapoor… - European journal of …, 2013 - academic.oup.com
Objective Men with type 2 diabetes are known to have a high prevalence of testosterone
deficiency. No long-term data are available regarding testosterone and mortality in men with …
deficiency. No long-term data are available regarding testosterone and mortality in men with …
Adverse effects of testosterone therapy in adult men: a systematic review and meta-analysis
MM Fernández-Balsells, MH Murad… - The Journal of …, 2010 - academic.oup.com
Context: The risks of testosterone therapy in men remain poorly understood. Objective: The
aim of this study was to conduct a systematic review and meta-analyses of testosterone trials …
aim of this study was to conduct a systematic review and meta-analyses of testosterone trials …
Cardiovascular risk associated with testosterone-boosting medications: a systematic review and meta-analysis
Introduction: Recent reports have significantly halted the enthusiasm regarding androgen-
boosting; suggesting that testosterone supplementation (TS) increases cardiovascular (CV) …
boosting; suggesting that testosterone supplementation (TS) increases cardiovascular (CV) …