[HTML][HTML] Tumor-associated macrophages regulate PD-1/PD-L1 immunosuppression
Y Pu, Q Ji - Frontiers in immunology, 2022 - frontiersin.org
Anti-programmed cell death 1 (PD-1) or anti-PD-ligand (L) 1 drugs, as classic immune
checkpoint inhibitors, are considered promising treatment strategies for tumors. In clinical …
checkpoint inhibitors, are considered promising treatment strategies for tumors. In clinical …
Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation
Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …
oncology treatments, emerges in the current management of cancer. A growing number of …
[HTML][HTML] Targeting macrophages: a novel treatment strategy in solid tumors
M Liu, L Liu, Y Song, W Li, L Xu - Journal of Translational Medicine, 2022 - Springer
In the tumor microenvironment (TME), tumor-associated macrophages (TAMs) are the most
abundant immune cells, which act as a key regulator in tumorigenesis and progression …
abundant immune cells, which act as a key regulator in tumorigenesis and progression …
[HTML][HTML] New therapeutics for HCC: Does tumor immune microenvironment matter?
A Khanam, S Kottilil - International Journal of Molecular Sciences, 2022 - mdpi.com
The incidence of liver cancer is continuously rising where hepatocellular carcinoma (HCC)
remains the most common form of liver cancer accounting for approximately 80–90% of the …
remains the most common form of liver cancer accounting for approximately 80–90% of the …
Nanozymes-engineered metal–organic frameworks for enhanced microwave thermodynamic therapy in PDX of hepatic carcinoma
Z Chen, Q Du, W Guo, H Huang, H Li, Y Zheng… - Chemical Engineering …, 2022 - Elsevier
Dynamic therapy (DT) has emerged as a promising cancer therapy due to its non-invasive
treatment and good spatiotemporal control. However, the efficiency of DT is restricted by …
treatment and good spatiotemporal control. However, the efficiency of DT is restricted by …
Remotely boosting hyaluronidase activity to normalize the hypoxic immunosuppressive tumor microenvironment for photothermal immunotherapy
Y Liu, D Xu, Y Liu, X Zheng, J Zang, W Ye, Y Zhao… - Biomaterials, 2022 - Elsevier
Tumor hyaluronan (HA) accumulation is closely associated with the formation of a hypoxic
microenvironment that is highly immunosuppressive and severely hinders the efficacy of …
microenvironment that is highly immunosuppressive and severely hinders the efficacy of …
Ultra-efficient radio-immunotherapy for reprogramming the hypoxic and immunosuppressive tumor microenvironment with durable innate immune memory
J Yang, C Zhang, X Chen, D Zhou, Z Sun, R Niu, Y Zhu… - Biomaterials, 2023 - Elsevier
Radiosensitization efficacy of conventional tumor radiosensitizers has been frequently
limited by insufficient competence for tumor microenvironment (TME) regulation and …
limited by insufficient competence for tumor microenvironment (TME) regulation and …
Nickel oxide nanoparticle synthesis and photocatalytic applications: evolution from conventional methods to novel microfluidic approaches
J Mou, Y Ren, J Wang, C Wang, Y Zou, K Lou… - Microfluidics and …, 2022 - Springer
Nickel oxide (NiO) nanoparticles are essential to developing a wide range of important
industrial products, examples of which include electrodes, catalysts, and sensors, leading to …
industrial products, examples of which include electrodes, catalysts, and sensors, leading to …
Current strategies for the treatment of hepatocellular carcinoma by modulating the tumor microenvironment via nano-delivery systems: a review
Y Huang, T Wang, J Yang, X Wu, W Fan… - International Journal of …, 2022 - Taylor & Francis
Liver cancer remains a global health challenge with a projected incidence of over one
million cases by 2025. Hepatocellular carcinoma (HCC) is a common primary liver cancer …
million cases by 2025. Hepatocellular carcinoma (HCC) is a common primary liver cancer …
Biocompatible snowman-like tumor-targeting dimer nanoparticles for improved delivery efficiency and enhanced anti-tumor therapy
C Ye, X Yan, X Dai, R Chen, Q Li, S Xu, Q Jiang… - Chemical Engineering …, 2023 - Elsevier
Chemotherapy is indispensable for the systematic treatment of aggressive malignancies,
such as pancreatic ductal adenocarcinoma (PDAC), while delivery vehicles are essential for …
such as pancreatic ductal adenocarcinoma (PDAC), while delivery vehicles are essential for …