Quantitative magnetic resonance imaging of brain anatomy and in vivo histology

N Weiskopf, LJ Edwards, G Helms… - Nature Reviews …, 2021 - nature.com
Quantitative magnetic resonance imaging (qMRI) goes beyond conventional MRI, which
aims primarily at local image contrast. It provides specific physical parameters related to the …

Traumatic and nontraumatic spinal cord injury: pathological insights from neuroimaging

G David, S Mohammadi, AR Martin… - Nature Reviews …, 2019 - nature.com
Pathophysiological changes in the spinal cord white and grey matter resulting from injury
can be observed with MRI techniques. These techniques provide sensitive markers of …

Apparent thinning of human visual cortex during childhood is associated with myelination

VS Natu, J Gomez, M Barnett, B Jeska… - Proceedings of the …, 2019 - National Acad Sciences
Human cortex appears to thin during childhood development. However, the underlying
microstructural mechanisms are unknown. Using functional magnetic resonance imaging …

GnRH replacement rescues cognition in Down syndrome

M Manfredi-Lozano, V Leysen, M Adamo, I Paiva… - Science, 2022 - science.org
At the present time, no viable treatment exists for cognitive and olfactory deficits in Down
syndrome (DS). We show in a DS model (Ts65Dn mice) that these progressive …

[HTML][HTML] Parkinson's disease multimodal imaging: F-DOPA PET, neuromelanin-sensitive and quantitative iron-sensitive MRI

F Depierreux, E Parmentier, L Mackels… - npj Parkinson's …, 2021 - nature.com
Parkinson's disease (PD) is a neurodegenerative synucleinopathy characterized by the
degeneration of neuromelanin (NM)-containing dopaminergic neurons and deposition of …

Convolutional neural network in medical image analysis: A review

SS Kshatri, D Singh - Archives of Computational Methods in Engineering, 2023 - Springer
Medical image analysis helps in resolving clinical issues by examining clinically generated
images. In today's world of deep learning (DL) along with advances in computer vision, the …

Timely coupling of sleep spindles and slow waves linked to early amyloid-β burden and predicts memory decline

D Chylinski, M Van Egroo, J Narbutas, V Muto… - Elife, 2022 - elifesciences.org
Sleep alteration is a hallmark of ageing and emerges as a risk factor for Alzheimer's disease
(AD). While the fine-tuned coalescence of sleep microstructure elements may influence age …

Multiparameter mapping of relaxation (R1, R2*), proton density and magnetization transfer saturation at 3 T: A multicenter dual‐vendor reproducibility and repeatability …

T Leutritz, M Seif, G Helms, RS Samson… - Human brain …, 2020 - Wiley Online Library
Multicenter clinical and quantitative magnetic resonance imaging (qMRI) studies require a
high degree of reproducibility across different sites and scanner manufacturers, as well as …

[HTML][HTML] Multiparametric quantitative MRI in neurological diseases

A Seiler, U Nöth, P Hok, A Reiländer… - Frontiers in …, 2021 - frontiersin.org
Magnetic resonance imaging (MRI) is the gold standard imaging technique for diagnosis
and monitoring of many neurological diseases. However, the application of conventional …

[HTML][HTML] The traveling heads 2.0: multicenter reproducibility of quantitative imaging methods at 7 Tesla

MN Voelker, O Kraff, S Goerke, FB Laun, J Hanspach… - Neuroimage, 2021 - Elsevier
Object This study evaluates inter-site and intra-site reproducibility at ten different 7 T sites for
quantitative brain imaging. Material and Methods Two subjects–termed the “traveling heads” …