Zebrafish as an alternative animal model in human and animal vaccination research

RL Bailone, HCS Fukushima… - Laboratory animal …, 2020 - Springer
Much of medical research relies on animal models to deepen knowledge of the causes of
animal and human diseases, as well as to enable the development of innovative therapies …

The functional RNA cargo of bacterial membrane vesicles

P Dauros-Singorenko, C Blenkiron… - FEMS microbiology …, 2018 - academic.oup.com
Bacteria secrete RNAs, some of which have effects on other cells and on other species as
signalling RNAs. Prokaryotic membrane vesicles (MVs) contain a range of RNA types. The …

Extended antibiotic treatment in salmon farms select multiresistant gut bacteria with a high prevalence of antibiotic resistance genes

S Higuera-Llantén, F Vásquez-Ponce… - PLoS …, 2018 - journals.plos.org
The high use of antibiotics for the treatment of bacterial diseases is one of the main
problems in the mass production of animal protein. Salmon farming in Chile is a clear …

Why Does Piscirickettsia salmonis Break the Immunological Paradigm in Farmed Salmon? Biological Context to Understand the Relative Control of Piscirickettsiosis

M Rozas-Serri - Frontiers in immunology, 2022 - frontiersin.org
Piscirickettsiosis (SRS) has been the most important infectious disease in Chilean salmon
farming since the 1980s. It was one of the first to be described, and to date, it continues to be …

Chilean aquaculture and the new challenges: Pathogens, immune response, vaccination and fish diversification

C Flores-Kossack, R Montero, B Köllner… - Fish & shellfish …, 2020 - Elsevier
In Chile, the salmon and trout farmed fishing industries have rapidly grown during the last
years, becoming one of the most important economic sources for the country. However …

Intracellular bacterial infections: a challenge for developing cellular mediated immunity vaccines for farmed fish

HM Munang'andu - Microorganisms, 2018 - mdpi.com
Aquaculture is one of the most rapidly expanding farming systems in the world. Its rapid
expansion has brought with it several pathogens infecting different fish species. As a result …

Outer membrane vesicles from Piscirickettsia salmonis induce the expression of inflammatory genes and production of IgM in Atlantic salmon Salmo salar

C Oliver, JL Coronado, D Martínez… - Fish & Shellfish …, 2023 - Elsevier
Piscirickettsiosis outbreaks due to Piscirickettsia salmonis occur globally in the Chilean
salmon aquaculture generating significant monetary losses in the industry. P. salmonis …

Horizontal gene transfer in bacteria, an overview of the mechanisms involved

TG Villa, L Feijoo-Siota, A Sánchez-Pérez… - Horizontal gene transfer …, 2019 - Springer
Bacterial transformation, transduction, and “conjugation” can be considered the first
horizontal transfer mechanisms in living organisms; these mechanisms have occurred since …

PAMPs of Piscirickettsia salmonis Trigger the Transcription of Genes Involved in Nutritional Immunity in a Salmon Macrophage-Like Cell Line

DP Martínez, C Oliver, N Santibañez… - Frontiers in …, 2022 - frontiersin.org
The innate immune system can limit the growth of invading pathogens by depleting
micronutrients at a cellular and tissue level. However, it is not known whether nutrient …

Proteome analysis of the Gram-positive fish pathogen Renibacterium salmoninarum reveals putative role of membrane vesicles in virulence

T Kroniger, D Flender, R Schlüter, B Köllner… - Scientific Reports, 2022 - nature.com
Bacterial kidney disease (BKD) is a chronic bacterial disease affecting both wild and farmed
salmonids. The causative agent for BKD is the Gram-positive fish pathogen Renibacterium …