Antimicrobial peptides: Promising alternatives in the post feeding antibiotic era

J Wang, X Dou, J Song, Y Lyu, X Zhu… - Medicinal research …, 2019 - Wiley Online Library
Antimicrobial peptides (AMPs), critical components of the innate immune system, are widely
distributed throughout the animal and plant kingdoms. They can protect against a broad …

[HTML][HTML] Antimicrobial peptides: new hope in the war against multidrug resistance

J Mwangi, X Hao, R Lai, ZY Zhang - Zoological research, 2019 - ncbi.nlm.nih.gov
The discovery of antibiotics marked a golden age in the revolution of human medicine.
However, decades later, bacterial infections remain a global healthcare threat, and a return …

Antimicrobial peptides: interaction with model and biological membranes and synergism with chemical antibiotics

A Hollmann, M Martinez, P Maturana… - Frontiers in …, 2018 - frontiersin.org
Antimicrobial peptides (AMPs) are promising novel antibiotics since they have shown
antimicrobial activity against a wide range of bacterial species, including multiresistant …

Antibiotic Resistance Profiles, Molecular Mechanisms and Innovative Treatment Strategies of Acinetobacter baumannii

CO Vrancianu, I Gheorghe, IB Czobor, MC Chifiriuc - Microorganisms, 2020 - mdpi.com
Antibiotic resistance is one of the biggest challenges for the clinical sector and industry,
environment and societal development. One of the most important pathogens responsible …

The chemistry and biological activities of peptides from amphibian skin secretions

X Xu, R Lai - Chemical reviews, 2015 - ACS Publications
Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …

Antimicrobial peptide synergies for fighting infectious diseases

JT Mhlongo, AY Waddad, F Albericio… - Advanced …, 2023 - Wiley Online Library
Antimicrobial peptides (AMPs) are essential elements of thehost defense system.
Characterized by heterogenous structures and broadspectrumaction, they are promising …

Antimicrobial peptides: an alternative for innovative medicines?

JP Da Costa, M Cova, R Ferreira, R Vitorino - Applied microbiology and …, 2015 - Springer
Antimicrobial peptides are small molecules with activity against bacteria, yeasts, fungi,
viruses, bacteria, and even tumor cells that make these molecules attractive as therapeutic …

Cationic antimicrobial peptides as novel cytotoxic agents for cancer treatment

JS Mader, DW Hoskin - Expert opinion on investigational drugs, 2006 - Taylor & Francis
Cancer treatment by conventional chemotherapy is hindered by toxic side effects and the
frequent development of multi-drug resistance by cancer cells. Cationic antimicrobial …

[HTML][HTML] Lipopolysaccharide (Endotoxin)-host defense antibacterial peptides interactions: role in bacterial resistance and prevention of sepsis

Y Rosenfeld, Y Shai - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2006 - Elsevier
Lipopolysaccharide (LPS) is the major molecular component of the outer membrane of Gram-
negative bacteria and serves as a physical barrier providing the bacteria protection from its …

De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers

S Choi, A Isaacs, D Clements, D Liu… - Proceedings of the …, 2009 - National Acad Sciences
The emergence of drug-resistant bacteria has compromised the use of many conventional
antibiotics, leading to heightened interest in a variety of antimicrobial peptides. Although …