The population genetics of pathogenic Escherichia coli

E Denamur, O Clermont, S Bonacorsi… - Nature Reviews …, 2021 - nature.com
Escherichia coli is a commensal of the vertebrate gut that is increasingly involved in various
intestinal and extra-intestinal infections as an opportunistic pathogen. Numerous pathotypes …

Reaching the end of the line: urinary tract infections

KO Tamadonfar, NS Omattage… - Microbiology …, 2019 - Am Soc Microbiol
Urinary tract infections (UTIs) cause a substantial health care burden. UTIs (i) are most often
caused by uropathogenic Escherichia coli (UPEC),(ii) primarily affect otherwise healthy …

[HTML][HTML] Population dynamics of an Escherichia coli ST131 lineage during recurrent urinary tract infection

BM Forde, LW Roberts, MD Phan, KM Peters… - Nature …, 2019 - nature.com
Recurrent urinary tract infections (rUTIs) are extremely common, with~ 25% of all women
experiencing a recurrence within 1 year of their original infection. Escherichia coli ST131 is …

The Challenge of Global Emergence of Novel Colistin-Resistant Escherichia coli ST131

M Taati Moghadam, M Mirzaei… - Microbial drug …, 2021 - liebertpub.com
Escherichia coli ST131 is one of the high-risk multidrug-resistant clones with a global
distribution and the ability to persist and colonize in a variety of niches. Carbapenemase …

Emergence of ESBL-producing Escherichia coli ST131-C1-M27 clade colonizing patients in Europe

I Merino, M Hernández-García… - Journal of …, 2018 - academic.oup.com
Abstract Background The ST131 Escherichia coli clone is associated with the global
dissemination of ESBLs. It has been hypothesized that ST131 could take advantage of better …

[HTML][HTML] E. coli catheter-associated urinary tract infections are associated with distinctive virulence and biofilm gene determinants

Z Zou, RF Potter, WH McCoy, JA Wildenthal… - JCI insight, 2023 - ncbi.nlm.nih.gov
Urinary catheterization facilitates urinary tract colonization by E. coli and increases infection
risk. Here, we aimed to identify strain-specific characteristics associated with the transition …

[HTML][HTML] Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract

CH Connor, AZ Zucoloto, JT Munnoch, IL Yu… - PLoS …, 2023 - journals.plos.org
Extra-intestinal pathogenic Escherichia coli (ExPEC) can cause a variety of infections
outside of the intestine and are a major causative agent of urinary tract infections. Treatment …

[HTML][HTML] Cryptosporidiosis modulates the gut microbiome and metabolism in a murine infection model

AV Karpe, ML Hutton, SJ Mileto, ML James, C Evans… - Metabolites, 2021 - mdpi.com
Cryptosporidiosis is a major human health concern globally. Despite well-established
methods, misdiagnosis remains common. Our understanding of the cryptosporidiosis …

[HTML][HTML] DegS protease regulates the motility, chemotaxis, and colonization of Vibrio cholerae

M Zou, K Wang, J Zhao, H Lu, H Yang… - Frontiers in …, 2023 - frontiersin.org
In bacteria, DegS protease functions as an activating factor of the σE envelope stress
response system, which ultimately activates the transcription of stress response genes in the …

[HTML][HTML] The pandemic Escherichia coli sequence type 131 strain is acquired even in the absence of antibiotic exposure

GR Whitmer, G Moorthy, M Arshad - PLoS pathogens, 2019 - journals.plos.org
Escherichia coli sequence type 131 (ST131) is a pandemic multidrug resistant (MDR) strain
that has had unprecedented global expansion in the last decade and is now the …