Interactions between Borrelia burgdorferi and ticks

C Kurokawa, GE Lynn, JHF Pedra, U Pal… - Nature Reviews …, 2020 - nature.com
Borrelia burgdorferi is the causative agent of Lyme disease and is transmitted to vertebrate
hosts by Ixodes spp. ticks. The spirochaete relies heavily on its arthropod host for basic …

The tick microbiome: why non-pathogenic microorganisms matter in tick biology and pathogen transmission

SI Bonnet, F Binetruy… - Frontiers in cellular …, 2017 - frontiersin.org
Ticks are among the most important vectors of pathogens affecting humans and other
animals worldwide. They do not only carry pathogens however, as a diverse group of …

Analysis of 1,000+ Type-Strain Genomes Substantially Improves Taxonomic Classification of Alphaproteobacteria

A Hördt, MG López, JP Meier-Kolthoff… - Frontiers in …, 2020 - frontiersin.org
The class Alphaproteobacteria is comprised of a diverse assemblage of Gram-negative
bacteria that includes organisms of varying morphologies, physiologies and habitat …

A high-quality Ixodes scapularis genome advances tick science

S De, SB Kingan, C Kitsou, DM Portik, SD Foor… - Nature Genetics, 2023 - nature.com
Ixodes spp. and related ticks transmit prevalent infections, although knowledge of their
biology and development of anti-tick measures have been hindered by the lack of a high …

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

M Gulia-Nuss, AB Nuss, JM Meyer… - Nature …, 2016 - nature.com
Ticks transmit more pathogens to humans and animals than any other arthropod. We
describe the 2.1 Gbp nuclear genome of the tick, Ixodes scapularis (Say), which vectors …

Cells within cells: Rickettsiales and the obligate intracellular bacterial lifestyle

J Salje - Nature Reviews Microbiology, 2021 - nature.com
The Rickettsiales are a group of obligate intracellular vector-borne Gram-negative bacteria
that include many organisms of clinical and agricultural importance, including Anaplasma …

Evolutionary changes in symbiont community structure in ticks

O Duron, F Binetruy, V Noël, J Cremaschi… - Molecular …, 2017 - Wiley Online Library
Ecological specialization to restricted diet niches is driven by obligate, and often maternally
inherited, symbionts in many arthropod lineages. These heritable symbionts typically form …

Grappling with the tick microbiome

S Narasimhan, A Swei, S Abouneameh, U Pal… - Trends in …, 2021 - cell.com
Ixodes scapularis and Ixodes pacificus are the predominant vectors of multiple human
pathogens, including Borrelia burgdorferi, one of the causative agents of Lyme disease in …

Human pathogens associated with the blacklegged tick Ixodes scapularis: a systematic review

MP Nelder, CB Russell, NJ Sheehan, B Sander… - Parasites & vectors, 2016 - Springer
Abstract Background The blacklegged tick Ixodes scapularis transmits Borrelia burgdorferi
(sensu stricto) in eastern North America; however, the agent of Lyme disease is not the sole …

Polymicrobial nature of tick-borne diseases

S Sanchez-Vicente, T Tagliafierro, JL Coleman… - MBio, 2019 - Am Soc Microbiol
Tick-borne diseases have doubled in the last 12 years, and their geographic distribution has
spread as well. The clinical spectrum of tick-borne diseases can range from asymptomatic to …