Current therapeutic strategies for stem cell‐based cartilage regeneration

Y Nam, YA Rim, J Lee, JH Ju - Stem cells international, 2018 - Wiley Online Library
The process of cartilage destruction in the diarthrodial joint is progressive and irreversible.
This destruction is extremely difficult to manage and frustrates researchers, clinicians, and …

Meniscus repair and regeneration: a systematic review from a basic and translational science perspective

J Twomey-Kozak… - Clinics in sports …, 2020 - sportsmed.theclinics.com
The meniscal injury is a major cause of functional impairment in the knee joint. This
fibrocartilaginous tissue was once considered to be an unnecessary, vestigial appendage …

Characterizing the effects of synergistic thermal and photo-cross-linking during biofabrication on the structural and functional properties of gelatin methacryloyl (GelMA …

P Chansoria, S Asif, K Polkoff, J Chung… - ACS Biomaterials …, 2021 - ACS Publications
Gelatin methacryloyl (GelMA) hydrogels have emerged as promising and versatile
biomaterial matrices with applications spanning drug delivery, disease modeling, and tissue …

Cartilage regeneration by chondrogenic induced adult stem cells in osteoarthritic sheep model

CC Ude, SB Sulaiman, N Min-Hwei, C Hui-Cheng… - PLoS …, 2014 - journals.plos.org
Objectives In this study, Adipose stem cells (ADSC) and bone marrow stem cells (BMSC),
multipotent adult cells with the potentials for cartilage regenerations were induced to …

Stem cell technology for bone regeneration: current status and potential applications

G Asatrian, D Pham, WR Hardy… - Stem cells and cloning …, 2015 - Taylor & Francis
Continued improvements in the understanding and application of mesenchymal stem cells
(MSC) have revolutionized tissue engineering. This is particularly true within the field of …

Recent progress in interfacial tissue engineering approaches for osteochondral defects

NJ Castro, SA Hacking, LG Zhang - Annals of biomedical engineering, 2012 - Springer
This review provides a brief synopsis of the anatomy and physiology of the osteochondral
interface, scaffold-based and non-scaffold based approaches for engineering both tissues …

Chondrogenic differentiation of adipose-derived mesenchymal stem cells induced by L-ascorbic acid and platelet rich plasma on silk fibroin scaffold

A Barlian, H Judawisastra, NM Alfarafisa, UA Wibowo… - PeerJ, 2018 - peerj.com
Articular cartilage is an avascular tissue with limited regenerative property. Therefore, a
defect or trauma in articular cartilage due to disease or accident can lead to progressive …

Edible Bird's nest extract as a chondro-protective agent for human chondrocytes isolated from osteoarthritic knee: in vitro study

KH Chua, TH Lee, K Nagandran… - … and alternative medicine, 2013 - Springer
Background Osteoarthritis (OA) is a degenerative joint disease that results in the destruction
of cartilage. Edible Bird's Nest (EBN) extract contains important components, which can …

From cells to organs: progress and potential in cartilaginous organoids research

X Wang, N Liu, H Zhang, Z Yin, ZG Zha - Journal of Translational Medicine, 2023 - Springer
While cartilage tissue engineering has significantly improved the speed and quality of
cartilage regeneration, the underlying metabolic mechanisms are complex, making research …

Induction of articular chondrogenesis by chitosan/hyaluronic-acid-based biomimetic matrices using human adipose-derived stem cells

Y Huang, D Seitz, F König, PE Müller… - International journal of …, 2019 - mdpi.com
Cartilage repair using tissue engineering is the most advanced clinical application in
regenerative medicine, yet available solutions remain unsuccessful in reconstructing native …