Pyridinones have been adopted as an important block in medicinal chemistry that could
serve as hydrogen bond donors and acceptors. With the help of feasible synthesis routes via …

Background The chemistry and applications of 2-pyridone structures have recently attracted
a lot of attention due to their uses as synthetic intermediates and their biological importance …

A hybrid pharmacophore approach was adopted to design and synthesize new series of
pyridone-thiazole hybrid compounds. The structures of the compounds were established by …

In this article, a series of benzothiazole-bearing N-sulfonamide 2-pyridone derivatives were
synthesized via the reaction of benzothiazole sulfonylhydrazide with sodium salts of both …

Ten new pyridine linked various substituted thiazole hybrids through (hydrazonomethyl)
phenoxy-acetamide spacer were synthesized. The synthetic strategy was based on the …

Pyridone core structure has attracted much attention due to its abundance in natural
products of biological importance. 2-Pyridone derivatives display diverse biological …

The observed toxicity of newly designed anticancer drugs is considered as an impediment
challenging phenomenon of intense concern arising from diversity in drug targets and the …

Derivatives with tetrahydrobenzo [h] quinoline chemotype were synthesized via one-pot
reactions and evaluated for their antileishmanial, antimalarial and antitubercular activities …

A practical and efficient solvent-free synthesis of β-trifluoromethyl-substituted phosphonates
and phosphine oxides via hydrophosphonylation and hydrophosphinylation of α …

A new efficient method for the direct alkenylation of chromones via a palladium (II)-catalyzed
C–H functionalization reaction was developed. The use of pivalic acid with Cu (OAc) …