Tumor vascularization occurs through several distinct biological processes, which not only
vary between tumor type and anatomic location, but also occur simultaneously within the …

Abnormal vasculature is one of the most conspicuous traits of tumor tissue, largely
contributing to tumor immune evasion. The deregulation mainly arises from the potentiated …

The development of therapeutics for effective treatments of retinal diseases is significantly
constrained by various biological barriers. We herein report a nanomedicine strategy to …

Biomolecular and physical cues of the extracellular matrix environment regulate collective
cell dynamics and tissue patterning. Nonetheless, how the viscoelastic properties of the …

Diabetic wound healing still faces great challenges due to the excessive inflammation, easy
infection, and impaired angiogenesis in wound beds. The immunoregulation of …

Abstract Development of topical bioactive formulations capable of overcoming the low
bioavailability of conventional eye drops is critically important for efficient management of …

Organoids are powerful models for studying tissue development, physiology, and disease.
However, current culture systems disrupt the inductive tissue-tissue interactions needed for …

Diabetic wound healing and angiogenesis remain a worldwide challenge for both clinic and
research. The use of adipose stromal cell derived exosomes delivered by bioactive dressing …

As the COVID-19 pandemic continues to spread, investigating the processes underlying the
interactions between SARS-CoV-2 and its hosts is of high importance. Here, we report the …

Tumor blood vessels are a key target for cancer therapeutic management. Tumor cells
secrete high levels of pro-angiogenic factors which contribute to the creation of an abnormal …