Obesity is a major health risk, with junk food consumption playing a central role in weight
gain, because of its high palatability and high-energy nutrients. The Cafeteria (CAF) diet …

Obesity is associated with changes in memory. Thus, the aim of this systematic review was
to investigate the physical exercise consequences on memory in obesity. A search was …

Many promising findings from pre-clinical research have failed to translate to the clinic due
to their inability to incorporate human disease co-morbidity. A variety of rodent diets and …

Understanding neuroadaptations involved in obesity is critical for developing new
approaches to treatment. Diet-induced neuroadaptations within the dorsal striatum have the …

Obesity increases inflammation, both peripherally and centrally, and exercise can
ameliorate some of the negative health outcomes associated with obesity. Within the brain …

Excessive intake of high-caloric diets as well as subsequent development of obesity and
diabetes mellitus may exert a wide range of unfavorable effects on the central nervous …

Background Diet-induced obesity is associated with premature cognitive decline. Elevated
consumption of fats and sugars in humans and rodents has been associated with deficits in …

Evidence suggests that obesity and overweight may be associated with severe brain
structural abnormalities and poor cognitive and functional outcomes in the general …

Type 2 diabetes has been linked to cognitive impairment, but its potential metabolic
mechanism is still unclear. The present study aimed to explore neuron–astrocyte metabolic …

Diabetes mellitus (DM) is a chronic disease characterized by elevated blood glucose levels
caused by a lack of insulin production (type 1 diabetes) or insulin resistance (type 2 …