Growing scientific literature data suggest that the intake of natural bioactive compounds
plays a critical role in preventing or reducing the occurrence of human chronic non …

Alzheimer's disease (AD) is one of the most common neurodegenerative disorders, with no
cure and preventive therapy. Misfolding and extracellular aggregation of Amyloid-β (Aβ) …

Amyloids result from the aggregation of a set of diverse proteins, due to either specific
mutations or promoting intra-or extra-cellular conditions. Structurally, they are rich in …

Protein misfolding and aggregation into fibrillar deposits is a common feature of a large
group of degenerative diseases affecting the central nervous system or peripheral organs …

Iridoids, which have beneficial health properties, include a wide group of cyclopentane [c]
pyran monoterpenoids present in plants and insects. The cleavage of the cyclopentane ring …

Non-communicable diseases (NCDs) have become the largest contributor to worldwide
morbidity and mortality. Among them, cancer and cardiovascular diseases (CVDs) are …

Introduction: Clinical trials and population studies indicate the healthy virtues of the
Mediterranean diet and its main lipid component, extra-virgin olive oil (EVOO). Olive leaves …

Abstract α-synuclein plays a key role in the pathogenesis of Parkinson's disease (PD); its
deposits are found as amyloid fibrils in Lewy bodies and Lewy neurites, the …

The main objective of this work was to review literature on compounds extracted from olive
tree leaves, such as simple phenols (hydroxytyrosol) and flavonoids (Apigenin, apigenin-7 …

Oleuropein aglycone (OleA), the most abundant polyphenol in extra virgin olive oil (EVOO),
and Hydroxythyrosol (HT), the OleA main metabolite, have attracted our interest due to their …