[HTML][HTML] Mesenchymal stem cell homing: the devil is in the details

JM Karp, GSL Teo - Cell stem cell, 2009 - cell.com
The study of MSC trafficking is clinically relevant for minimally invasive cell therapy to
promote regeneration of damaged tissue, to treat inflammation, and to promote …

Mesenchymal stem cells for the treatment of neurodegenerative disease

N Joyce, G Annett, L Wirthlin, S Olson… - Regenerative …, 2010 - Taylor & Francis
Mesenchymal stem cells/marrow stromal cells (MSCs) present a promising tool for cell
therapy, and are currently being tested in US FDA-approved clinical trials for myocardial …

Intracerebral transplantation of bone marrow-derived mesenchymal stem cells reduces amyloid-beta deposition and rescues memory deficits in Alzheimer's disease …

JK Lee, HK Jin, S Endo, EH Schuchman, JE Carter… - Stem …, 2010 - academic.oup.com
Alzheimer's disease (AD) is characterized by the deposition of amyloid-β peptide (Aβ) and
the formation of neurofibrillary tangles. Transplantation of bone marrow-derived …

[HTML][HTML] A holistic view on c-Kit in cancer: Structure, signaling, pathophysiology and its inhibitors

S Pathania, OT Pentikäinen, PK Singh - Biochimica et Biophysica Acta …, 2021 - Elsevier
Receptor tyrosine kinases play an important role in many cellular processes, and their
dysregulation leads to diseases, most importantly cancer. One such receptor tyrosine kinase …

Therapeutic utility of mesenchymal stromal cell (MSC)-based approaches in chronic neurodegeneration: a glimpse into underlying mechanisms, current status, and …

M Rahbaran, AO Zekiy, M Bahramali… - Cellular & Molecular …, 2022 - Springer
Recently, mesenchymal stromal cell (MSC)-based therapy has become an appreciated
therapeutic approach in the context of neurodegenerative disease therapy. Accordingly, a …

Bone marrow-derived mesenchymal stem cells reduce brain amyloid-β deposition and accelerate the activation of microglia in an acutely induced Alzheimer's disease …

JK Lee, HK Jin, J Bae - Neuroscience letters, 2009 - Elsevier
The therapeutic potential of bone marrow-derived mesenchymal stem cells (BM-MSCs) has
recently been explored in various pathological conditions of the central nervous system …

The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease

HJ Lee, JK Lee, H Lee, J Shin, JE Carter… - Neuroscience …, 2010 - Elsevier
The neuropathological hallmarks of Alzheimer's disease (AD) include the presence of
extracellular amyloid-β peptide (Aβ) in the form of amyloid plaques in the brain parenchyma …

Adult cell therapy for brain neuronal damages and the role of tissue engineering

GJR Delcroix, PC Schiller, JP Benoit… - Biomaterials, 2010 - Elsevier
No long term effective treatments are currently available for brain neurological disorders
such as stroke/cerebral ischemia, traumatic brain injury and neurodegenerative disorders …

Transplantation of undifferentiated human mesenchymal stem cells protects against 6-hydroxydopamine neurotoxicity in the rat

F Blandini, L Cova, MT Armentero… - Cell …, 2010 - journals.sagepub.com
Stem cells have been increasingly recognized as a potential tool to replace or support cells
damaged by the neurodegenerative process that underlies Parkinson's disease (PD). In this …

Chimerization of astroglial population in the lumbar spinal cord after mesenchymal stem cell transplantation prolongs survival in a rat model of amyotrophic lateral …

C Boucherie, S Schäfer… - Journal of …, 2009 - Wiley Online Library
Adult mesenchymal stem cells (MSCs) exhibit neuroprotective properties when introduced
into the degenerating central nervous system through different putative mechanisms …