[HTML][HTML] Mesenchymal stem cell homing: the devil is in the details
The study of MSC trafficking is clinically relevant for minimally invasive cell therapy to
promote regeneration of damaged tissue, to treat inflammation, and to promote …
promote regeneration of damaged tissue, to treat inflammation, and to promote …
Mesenchymal stem cells for the treatment of neurodegenerative disease
N Joyce, G Annett, L Wirthlin, S Olson… - Regenerative …, 2010 - Taylor & Francis
Mesenchymal stem cells/marrow stromal cells (MSCs) present a promising tool for cell
therapy, and are currently being tested in US FDA-approved clinical trials for myocardial …
therapy, and are currently being tested in US FDA-approved clinical trials for myocardial …
Intracerebral transplantation of bone marrow-derived mesenchymal stem cells reduces amyloid-beta deposition and rescues memory deficits in Alzheimer's disease …
JK Lee, HK Jin, S Endo, EH Schuchman, JE Carter… - Stem …, 2010 - academic.oup.com
Alzheimer's disease (AD) is characterized by the deposition of amyloid-β peptide (Aβ) and
the formation of neurofibrillary tangles. Transplantation of bone marrow-derived …
the formation of neurofibrillary tangles. Transplantation of bone marrow-derived …
[HTML][HTML] A holistic view on c-Kit in cancer: Structure, signaling, pathophysiology and its inhibitors
Receptor tyrosine kinases play an important role in many cellular processes, and their
dysregulation leads to diseases, most importantly cancer. One such receptor tyrosine kinase …
dysregulation leads to diseases, most importantly cancer. One such receptor tyrosine kinase …
Therapeutic utility of mesenchymal stromal cell (MSC)-based approaches in chronic neurodegeneration: a glimpse into underlying mechanisms, current status, and …
M Rahbaran, AO Zekiy, M Bahramali… - Cellular & Molecular …, 2022 - Springer
Recently, mesenchymal stromal cell (MSC)-based therapy has become an appreciated
therapeutic approach in the context of neurodegenerative disease therapy. Accordingly, a …
therapeutic approach in the context of neurodegenerative disease therapy. Accordingly, a …
Bone marrow-derived mesenchymal stem cells reduce brain amyloid-β deposition and accelerate the activation of microglia in an acutely induced Alzheimer's disease …
The therapeutic potential of bone marrow-derived mesenchymal stem cells (BM-MSCs) has
recently been explored in various pathological conditions of the central nervous system …
recently been explored in various pathological conditions of the central nervous system …
The therapeutic potential of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer's disease
HJ Lee, JK Lee, H Lee, J Shin, JE Carter… - Neuroscience …, 2010 - Elsevier
The neuropathological hallmarks of Alzheimer's disease (AD) include the presence of
extracellular amyloid-β peptide (Aβ) in the form of amyloid plaques in the brain parenchyma …
extracellular amyloid-β peptide (Aβ) in the form of amyloid plaques in the brain parenchyma …
Adult cell therapy for brain neuronal damages and the role of tissue engineering
GJR Delcroix, PC Schiller, JP Benoit… - Biomaterials, 2010 - Elsevier
No long term effective treatments are currently available for brain neurological disorders
such as stroke/cerebral ischemia, traumatic brain injury and neurodegenerative disorders …
such as stroke/cerebral ischemia, traumatic brain injury and neurodegenerative disorders …
Transplantation of undifferentiated human mesenchymal stem cells protects against 6-hydroxydopamine neurotoxicity in the rat
F Blandini, L Cova, MT Armentero… - Cell …, 2010 - journals.sagepub.com
Stem cells have been increasingly recognized as a potential tool to replace or support cells
damaged by the neurodegenerative process that underlies Parkinson's disease (PD). In this …
damaged by the neurodegenerative process that underlies Parkinson's disease (PD). In this …
Chimerization of astroglial population in the lumbar spinal cord after mesenchymal stem cell transplantation prolongs survival in a rat model of amyotrophic lateral …
C Boucherie, S Schäfer… - Journal of …, 2009 - Wiley Online Library
Adult mesenchymal stem cells (MSCs) exhibit neuroprotective properties when introduced
into the degenerating central nervous system through different putative mechanisms …
into the degenerating central nervous system through different putative mechanisms …