Metformin, the most prescribed antidiabetic medicine, has shown other benefits such as anti-
ageing and anticancer effects,,–. For clinical doses of metformin, AMP-activated protein …

Nonalcoholic fatty liver disease (NAFLD) is a global epidemic that is likely to become the
most common cause of chronic liver disease in the next decade, worldwide. Though …

Lipid metabolism is an important and complex biochemical process involved in the storage
of energy and maintenance of normal biological functions. Leucine, a branched amino acid …

Obesity is most commonly defined as a BMI of over 30kg/m2. Typical classification is into
categories of Class I (BMI> 30 kg/m2), Class II (BMI equal to or over 35 kg/m2) and Class III …

Branched chain amino acids (BCAAs), especially leucine (Leu), have been reported to
decrease fat deposition. However, extensive studies have not been conducted to determine …

Obesity develops from an imbalance of energy homeostasis and is associated with chronic
low-grade inflammation in white adipose tissues (WAT). Inflammation is involved in the …

Obesity increases the risk of developing insulin resistance and diabetes and is a major
public health concern. Our previous study shows that dietary β‐hydroxy‐β‐methylbutyrate …

This issue of “Metabolism, Clinical and Experimental” is devoted to nonalcoholic fatty liver
disease (NAFLD), a disease of alarmingly increasing prevalence, linked to metabolic …

In the present study, the increasing demand for the by‐products of rice and wheat, especially
their bran part obtained by milling has been discussed along with their properties in …

Summary Background Sirtuin 1 (Sirt1) is suppressed in non‐alcoholic fatty liver disease
(NAFLD), while its' stimulation or overexpression results in reduced disease severity in pre …