lipoxygenase (12/15-LOX) is an enzyme, which oxidizes polyunsaturated fatty acids,
particularly omega-6 and-3 fatty acids, to generate a number of bioactive lipid metabolites. A …

Lipoxygenases (LOX) form a family of lipid peroxidizing enzymes, which have been
implicated in a number of physiological processes and in the pathogenesis of inflammatory …

The notion that electrophiles serve as messengers in cell signaling is now widely accepted.
Nonetheless, major issues restrain acceptance of redox homeostasis and redox signaling as …

The reaction specificity of lipoxygenases (ALOX) impacts the biological activity of these
enzymes and also constitutes the decisive parameter for enzyme classification. ALOX15 …

ALOX15 (12/15-lipoxygenase) orthologs have been implicated in maturational degradation
of intracellular organelles and in the biosynthesis of antiinflammatory and proresolving …

Abstract Arachidonic acid 15-lipoxygenase (ALOX15), as one of the lipoxygenase family, is
mainly responsible for catalyzing the oxidation of various fatty acids to produce a variety of …

Arachidonic acid lipoxygenases (ALOXs) have been implicated in the immune response of
mammals. The reaction specificity of these enzymes is decisive for their biological functions …

Arachidonic acid lipoxygenases (ALOXs) are lipid-metabolizing enzymes that have been
implicated in cell differentiation, but also in the pathogenesis of inflammatory …

Lipoxygenases (ALOXs) are involved in the regulation of cellular redox homeostasis. They
also have been implicated in the biosynthesis of pro-and anti-inflammatory lipid mediators …

Lipoxygenases are lipid peroxidizing enzymes, which frequently occur in higher plants and
mammals. These enzymes are also expressed in lower multicellular organisms but here …