[HTML][HTML] Multi-drug resistant Mycobacterium tuberculosis & oxidative stress complexity: Emerging need for novel drug delivery approaches

K Dua, VK Rapalli, SD Shukla, G Singhvi… - Biomedicine & …, 2018 - Elsevier
Tuberculosis (caused by Mycobacterium tuberculosis, Mtb) treatment involves multiple drug
regimens for a prolonged period. However, the therapeutic benefit is often limited by poor …

Application of liposomes in the treatment of infectious diseases

NAA Suhaimi, S Ahmad, SMN Husna, ME Sarmiento… - Life Sciences, 2022 - Elsevier
The advances in the development of drugs and vaccines for major infectious diseases of
tuberculosis (TB), malaria and HIV represent some of the most significant milestones in their …

Cationic nanostructures for vaccines design

AM Carmona-Ribeiro, Y Pérez-Betancourt - Biomimetics, 2020 - mdpi.com
Subunit vaccines rely on adjuvants carrying one or a few molecular antigens from the
pathogen in order to guarantee an improved immune response. However, to be effective, the …

The effect of a TLR4 agonist/cationic liposome adjuvant on varicella-zoster virus glycoprotein E vaccine efficacy: antigen presentation, uptake, and delivery to lymph …

SR Wui, A Ko, JI Ryu, E Sim, SJ Lim, SA Park, KS Kim… - Pharmaceutics, 2021 - mdpi.com
Adjuvant CIA09, composed of 1, 2-dioleoyl-3-trimethylammonium-propane (DOTAP)-based
cationic liposomes and the toll-like receptor 4 agonist de-O-acylated lipooligosaccharide …

Plant-Produced N-glycosylated Ag85A Exhibits Enhanced Vaccine Efficacy Against Mycobacterium tuberculosis HN878 Through Balanced Multifunctional Th1 T Cell …

H Kim, KW Kwon, J Park, H Kang, Y Lee, EJ Sohn… - Vaccines, 2020 - mdpi.com
Tuberculosis (TB) is one of the deadliest infectious diseases worldwide and is caused by
Mycobacterium tuberculosis (Mtb). An effective vaccine to prevent TB is considered the most …

[HTML][HTML] Latest comprehensive knowledge of the crosstalk between TLR signaling and mycobacteria and the antigens driving the process

JS Kim, YR Kim, CS Yang - 2019 - jmb.or.kr
Tuberculosis, which is caused by Mycobacterium tuberculosis (Mtb), is among the most
pressing worldwide problems. Mtb uniquely interacts with innate immune cells through …

Immunogenicity of Recombinant Lipid-Based Nanoparticle Vaccines: Danger Signal vs. Helping Hand

V Temchura, JT Wagner, D Damm - Pharmaceutics, 2023 - mdpi.com
Infectious diseases are a predominant problem in human health. While the incidence of
many pathogenic infections is controlled by vaccines, some pathogens still pose a …

BCG-booster vaccination with HSP90-ESAT-6-HspX-RipA multivalent subunit vaccine confers durable protection against hypervirulent Mtb in mice

KW Kwon, HG Choi, KS Kim, SA Park, HJ Kim, SJ Shin - npj Vaccines, 2024 - nature.com
The quest for effective and enhanced multiantigenic tuberculosis (TB) subunit vaccine
necessitates the induction of a protective pathogen-specific immune response while …

[HTML][HTML] Performance of homologous and heterologous prime-boost immunization regimens of recombinant adenovirus and modified vaccinia virus ankara expressing …

Y Kou, M Wan, W Shi, J Liu, Z Zhao, Y Xu, W Wei… - 2018 - jmb.or.kr
Tuberculosis (TB) remains a serious health issue around the word. Adenovirus (Ad)-based
vaccine and modified vaccinia virus Ankara (MVA)-based vaccine have emerged as two of …

Nanotechnology-Based Vaccination for TB

A Barik, S Dey - Infectious Diseases Drug Delivery Systems, 2023 - Springer
With a projected global target to end the tuberculosis epidemic by the year 2030, United
Nations termed this as an important Sustainable Development Goal (SDG). Following …