The E factor at 30: a passion for pollution prevention

RA Sheldon - Green Chemistry, 2023 - pubs.rsc.org
The introduction of the E Factor in 1992 focussed attention on the problem of waste
generation, defined as everything but the desired product, in chemicals manufacture and …

[HTML][HTML] Biocatalysis

EL Bell, W Finnigan, SP France, AP Green… - Nature Reviews …, 2021 - nature.com
Biocatalysis has become an important aspect of modern organic synthesis, both in
academia and across the chemical and pharmaceutical industries. Its success has been …

Biocatalysis: enzymatic synthesis for industrial applications

S Wu, R Snajdrova, JC Moore… - Angewandte Chemie …, 2021 - Wiley Online Library
Biocatalysis has found numerous applications in various fields as an alternative to chemical
catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for …

Shortening synthetic routes to small molecule active pharmaceutical ingredients employing biocatalytic methods

S Simić, E Zukić, L Schmermund, K Faber… - Chemical …, 2021 - ACS Publications
Biocatalysis, using enzymes for organic synthesis, has emerged as powerful tool for the
synthesis of active pharmaceutical ingredients (APIs). The first industrial biocatalytic …

Biocatalysis making waves in organic chemistry

U Hanefeld, F Hollmann, CE Paul - Chemical Society Reviews, 2022 - pubs.rsc.org
Biocatalysis has an enormous impact on chemical synthesis. The waves in which
biocatalysis has developed, and in doing so changed our perception of what organic …

New frontiers in enzyme immobilisation: robust biocatalysts for a circular bio-based economy

RA Sheldon, A Basso, D Brady - Chemical Society Reviews, 2021 - pubs.rsc.org
This tutorial review focuses on recent advances in technologies for enzyme immobilisation,
enabling their cost-effective use in the bio-based economy and continuous processing in …

Power of biocatalysis for organic synthesis

CK Winkler, JH Schrittwieser, W Kroutil - ACS central science, 2021 - ACS Publications
Biocatalysis, using defined enzymes for organic transformations, has become a common
tool in organic synthesis, which is also frequently applied in industry. The generally high …

Design of an in vitro biocatalytic cascade for the manufacture of islatravir

MA Huffman, A Fryszkowska, O Alvizo, M Borra-Garske… - Science, 2019 - science.org
Enzyme-catalyzed reactions have begun to transform pharmaceutical manufacturing,
offering levels of selectivity and tunability that can dramatically improve chemical synthesis …

Biomass-based biorefineries: an important architype towards a circular economy

B Kumar, P Verma - Fuel, 2021 - Elsevier
Fossil based resources are a major contributor to energy and chemicals to modern-day
development. The negative environmental impacts of fossil-based resources accompanied …

Enzyme co-immobilization: Always the biocatalyst designers' choice… or not?

S Arana-Peña, D Carballares… - Biotechnology …, 2021 - Elsevier
The increasing relevance of cascade reactions in biocatalysis has sparked a great interest
for enzyme co-immobilization. Enzyme co-immobilization allows access to some kinetic …