Elective management of the neck in oral cavity squamous carcinoma: current concepts supported by prospective studies

A Ferlito, CE Silver, A Rinaldo - British Journal of Oral and Maxillofacial …, 2009 - Elsevier
The incidence of occult cervical metastasis in oral cavity cancer, even in early stages, is
significant, necessitating elective treatment of the neck in a majority of cases. There is no …

Infrared fluorescence-guided surgery for tumor and metastatic lymph node detection in head and neck cancer

HW White, AB Naveed, BR Campbell, YJ Lee… - Radiology: Imaging …, 2024 - pubs.rsna.org
In patients with head and neck cancer (HNC), surgical removal of cancerous tissue presents
the best overall survival rate. However, failure to obtain negative margins during resection …

Tumour infiltration depth⩾ 4 mm is an indication for an elective neck dissection in pT1cN0 oral squamous cell carcinoma

LJ Melchers, E Schuuring, BAC Van Dijk, GH De Bock… - Oral oncology, 2012 - Elsevier
Patients with pT1cN0 oral squamous cell carcinomas (OSCC) are generally not treated with
a neck dissection (ND). However, in 25% of cN0 patients, nodal metastases become …

The effect of occult nodal metastases on survival and regional control in patients with head and neck squamous cell carcinoma

CG Gourin, BT Conger, ES Porubsky… - The …, 2008 - Wiley Online Library
Objectives: To determine factors associated with disease‐free survival (DFS) and regional
control in clinically node‐negative head and neck squamous cell cancer (HNSCC) patients …

Positron emission tomography/computerized tomography (PET/CT) scanning for preoperative staging of patients with oral/head and neck cancer

C Nahmias, ER Carlson, LD Duncan… - Journal of oral and …, 2007 - Elsevier
PURPOSE: To investigate the role of 18-fluorine-fluorodeoxyglucose positron emission
tomography/computerized tomography (18F-FDG PET/CT) in the preoperative prediction of …

Incidence of oral cancer occult metastasis and survival of T1-T2N0 oral cancer patients

IA El-Naaj, Y Leiser, M Shveis, E Sabo… - Journal of oral and …, 2011 - Elsevier
PURPOSE: In head and neck cancer, the most important prognostic factor is the presence or
absence of neck metastasis. Although still debated in the published data regarding the “wait …

Detection of metastatic head and neck squamous cell carcinoma using the relative expression of tissue-specific mir-205

AM Fletcher, AC Heaford, DK Trask - Translational oncology, 2008 - Elsevier
The presence of cervical lymph node metastases in head and neck squamous cell
carcinoma (HNSCC) is the strongest determinant of patient prognosis. Owing to the impact …

Urokinase-Type Plasminogen Activator Receptor (uPAR) Expression and [64Cu]Cu-DOTA-AE105 uPAR-PET/CT in Patient-Derived Xenograft Models of Oral …

M Lawaetz, T Binderup, A Christensen, K Juhl… - Molecular Imaging and …, 2023 - Springer
Abstract Purpose [64Cu] Cu-DOTA-AE105 urokinase-type plasminogen activator receptor
(uPAR)-PET/CT is a novel and promising imaging modality for cancer visualization, although …

Lymph node metastasis: A bearing on prognosis in squamous cell carcinoma

C Kapoor, S Vaidya, V Wadhwan… - Indian journal of cancer, 2015 - journals.lww.com
Nodal status is a significant predictor for survival of patients with oral squamous cell
carcinoma (SCC), sentinel lymph node (SLN) biopsy, step sectioning of SLNs, and …

Clinical evaluation of a new molecular method for detection of micrometastases in head and neck squamous cell carcinoma

CG Shores, X Yin, W Funkhouser… - … –Head & Neck Surgery, 2004 - jamanetwork.com
Objective To better detect occult cervical metastases. Design RNA from 153 cervical lymph
nodes was analyzed for the presence of squamous cell carcinoma using quantitative …