Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …

For many decades, the thiazole moiety has been an important heterocycle in the world of
chemistry. The thiazole ring consists of sulfur and nitrogen in such a fashion that the pi (π) …

Thiazole, a five-membered heteroaromatic ring, is an important scaffold of a large number of
synthetic compounds. Its diverse pharmacological activity is reflected in many clinically …

Introduction Hybrid drug design has developed as a prime method for the development of
novel anticancer therapies that can theoretically solve much of the pharmacokinetic …

The cytotoxic activities of the compounds were determined by the 3‐(4, 5‐dimethylthiazolyl‐
2)‐2, 5‐diphenyltetrazolium bromide (MTT) method in human breast cancer (MCF‐7) …

Thiazole, a five-membered heterocyclic compound constitutes the skeleton of various
commercially marketed drug candidates and the heart-core in a diverse range of entities of …

A novel series of pyrazolyl chalcones containing quinoline scaffold, 5 av has been
synthesized by Claisen Schimdt condensation of aromatic acetophenone with 1-(4 …

Due to unavailability of a specific drug/vaccine to attenuate severe acute respiratory
syndrome coronavirus 2, the current strategy to combat the infection has been largely …

COVID-19 is a global health emergency that causes serious concerns. A global effort is
underway to identify drugs for the treatment of COVID-19. One possible solution to the …

The research explores the synthesis of a series of novel hybrid quinazolin-2, 4-dione
analogs bearing acetyl/amide bridged-nitrogen heterocyclic moieties such as azetidinone …