Mesenchymal stem cells: a potential therapeutic strategy for neurodegenerative diseases

P Yao, L Zhou, L Zhu, B Zhou, Q Yu - European Neurology, 2020 - karger.com
Neurodegenerative disease is a kind of chronic, progressive nervous system disease
characterized by neuron degeneration or apoptosis. Current treatments cannot prevent the …

Application of mesenchymal stem cells (MSCs) in neurodegenerative disorders: history, findings, and prospective challenges

N Biglari, A Mehdizadeh, MV Mastanabad… - … -Research and Practice, 2023 - Elsevier
Over the past few decades, the application of mesenchymal stem cells has captured the
attention of researchers and practitioners worldwide. These cells can be obtained from …

Update on the application of mesenchymal stem cell-derived exosomes in the treatment of Parkinson's disease: a systematic review

S Liu, L Li, J Zhuang, M Li, L Ye, X Chen, S Lin… - Frontiers in …, 2022 - frontiersin.org
Parkinson's disease (PD) has become the second largest neurodegenerative disease after
Alzheimer's disease, and its incidence is increasing year by year. Traditional dopamine …

Effects of mesenchymal stem cell on dopaminergic neurons, motor and memory functions in animal models of Parkinson's disease: a systematic review and meta …

JM Park, M Rahmati, SC Lee, JI Shin… - Neural Regeneration …, 2024 - journals.lww.com
Parkinson's disease is characterized by the loss of dopaminergic neurons in the substantia
nigra pars compacta, and although restoring striatal dopamine levels may improve …

Emerging point‐of‐care autologous cellular therapy using adipose‐derived stromal vascular fraction for neurodegenerative diseases

R Al‐kharboosh, JJ Perera, A Bechtle… - Clinical and …, 2022 - Wiley Online Library
Neurodegenerative disorders are characterized by the gradual decline and irreversible loss
of cognitive functions and CNS structures. As therapeutic recourse stagnates …

Neuroprotective effects of coenzyme Q10 in Parkinson's model via a novel Q10/miR-149-5p/MMPs pathway

E Ghasemloo, H Mostafavi, M Hosseini… - Metabolic brain …, 2021 - Springer
Parkinson's disease (PD) is a complex neurodegenerative disease in which the
understanding of the underlying molecular mechanisms can be constructive in the diagnosis …

Mesenchymal stem cell-based therapy for lysosomal storage diseases and other neurodegenerative disorders

SS Issa, AA Shaimardanova, VV Valiullin… - Frontiers in …, 2022 - frontiersin.org
Lysosomal storage diseases (LSDs) are a group of approximately 50 genetic disorders
caused by mutations in genes coding enzymes that are involved in cell degradation and …

[HTML][HTML] Role of mesenchymal stem cell-derived exosomes in the regeneration of different tissues

D Huang, H Shen, F Xie, D Hu, Q Jin… - Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Exosomes are nanovesicles with multiple components used in several applications.
Mesenchymal stem cells (MSCs) are well known for their great potential in clinical …

Therapeutic potentials of human microfluidic encapsulated conjunctival mesenchymal stem cells on the rat model of Parkinson's disease

M Forouzandeh, MR Bigdeli, H Mostafavi… - Experimental and …, 2021 - Elsevier
Background and aim Parkinson's disease (PD) is a progressive neurodegenerative disorder
caused by the destruction of the dopaminergic neurons in the nigrostriatal pathway, leading …

[HTML][HTML] The Potential of Mesenchymal Stem Cells in Treating Spinocerebellar Ataxia: Advances and Future Directions

GB Lee, SM Park, UJ Jung, SR Kim - Biomedicines, 2024 - mdpi.com
Spinocerebellar ataxia (SCA) is a heterogeneous disorder characterized by impaired
balance and coordination caused by cerebellar dysfunction. The absence of treatments …