Progress in the Application of Drugs for the Treatment of Multiple Sclerosis
W Wei, D Ma, L Li, L Zhang - Frontiers in Pharmacology, 2021 - frontiersin.org
Multiple sclerosis (MS) is an autoimmune and chronic inflammatory demyelinating disease
of the central nervous system (CNS), which gives rise to focal lesion in CNS and cause …
of the central nervous system (CNS), which gives rise to focal lesion in CNS and cause …
[HTML][HTML] Multiple sclerosis, the microbiome, TLR2, and the hygiene hypothesis
NJ Wasko, F Nichols, RB Clark - Autoimmunity reviews, 2020 - Elsevier
The pathophysiology of autoimmune diseases such as Multiple Sclerosis (MS) involves a
complex interaction between genetic and environmental factors. Studies of monozygotic …
complex interaction between genetic and environmental factors. Studies of monozygotic …
Leukemia inhibitory factor regulates Schwann cell proliferation and migration and affects peripheral nerve regeneration
Q Chen, Q Liu, Y Zhang, S Li, S Yi - Cell Death & Disease, 2021 - nature.com
Leukemia inhibitory factor (LIF) is a pleiotropic cytokine that stimulates neuronal
development and survival. Our previous study has demonstrated that LIF mRNA is …
development and survival. Our previous study has demonstrated that LIF mRNA is …
Systemic TLR2 tolerance enhances central nervous system remyelination
NJ Wasko, MH Kulak, D Paul, AM Nicaise… - Journal of …, 2019 - Springer
Background Multiple sclerosis (MS) is a central nervous system (CNS) autoimmune disease
characterized by both inflammatory demyelination and impaired remyelination. Studies …
characterized by both inflammatory demyelination and impaired remyelination. Studies …
Leukemia inhibitory factor: Recent advances and implications in biotechnology
Leukemia inhibitory factor (LIF) is a pleiotropic cytokine with several functions in health and
disease ranging from inflammation to cancer. LIF is also a potential target and/or therapeutic …
disease ranging from inflammation to cancer. LIF is also a potential target and/or therapeutic …
From Immunity to Neurogenesis: Toll-like Receptors as Versatile Regulators in the Nervous System
DM Abarca-Merlin, JA Martínez-Durán… - International Journal of …, 2024 - mdpi.com
Toll-like receptors (TLRs) are among the main components of the innate immune system.
They can detect conserved structures in microorganisms and molecules associated with …
They can detect conserved structures in microorganisms and molecules associated with …
[HTML][HTML] Delivery of Neuroregenerative Proteins to the Brain for Treatments of Neurodegenerative Brain Diseases
ET Ebert, KM Schwinghamer, TJ Siahaan - Life, 2024 - mdpi.com
Neurodegenerative brain diseases such as Alzheimer's disease (AD), multiple sclerosis
(MS), and Parkinson's disease (PD) are difficult to treat. Unfortunately, many therapeutic …
(MS), and Parkinson's disease (PD) are difficult to treat. Unfortunately, many therapeutic …
[图书][B] The Role of TLR2 Tolerance in Remyelination Following Cuprizone-Induced Myelin Injury
NJ Wasko - 2021 - search.proquest.com
Multiple sclerosis (MS) is a central nervous system (CNS) autoimmune disease
characterized by both inflammatory demyelination and impaired remyelination. Studies …
characterized by both inflammatory demyelination and impaired remyelination. Studies …