Annulated Heterocyclic[g]Coumarin Composites: Synthetic Approaches and Bioactive Profiling

N Mazin Zeki, Y Fakri Mustafa - Chemistry & Biodiversity, 2024 - Wiley Online Library
Coumarins, widely abundant natural heterocyclic compounds, are extensively employed in
creating various biologically and pharmacologically potent substances. The hybridization of …

Coumarin hybrids: a sighting of their roles in drug targeting

NM Zeki, YF Mustafa - Chemical Papers, 2024 - Springer
Phytocoumarins exhibit a range of biological activities, including antibacterial, anti-
inflammatory, antiradical, oncolytic, and reduction of monoamine oxidase B effects. These …

Coumarin hybrids for targeted therapies: A promising approach for potential drug candidates

NM Zeki, YF Mustafa - Phytochemistry Letters, 2024 - Elsevier
Phyto-coumarins demonstrate diverse biological actions, encompassing antiradical, anti-
inflammatory, oncolytic, monoamine oxidase B (MAOB) suppression, and antibacterial …

Synthesis and evaluation of novel ring-conjugated coumarins as biosafe broad-spectrum antimicrobial candidates

NM Zeki, YF Mustafa - Journal of Molecular Structure, 2024 - Elsevier
This study presents, for the first time, the synthesis of innovative conjugates identified as a
five-membered ring integrating three heteroatoms linked linearly to the coumarin framework …

Exploring novel pyrazole-nitroimidazole hybrids: Synthesis and antiprotozoal activity against the human pathogen trichomonas vaginalis

RC Silva, A De Freitas, B Vicente, V Midlej… - Bioorganic & Medicinal …, 2024 - Elsevier
Trichomoniasis, a prevalent sexually transmitted infection (STI) caused by the protozoan
Trichomonas vaginalis, has gained increased significance globally. Its relevance has grown …

New pyridine‐based chalcones and pyrazolines with anticancer, antibacterial, and antiplasmodial activities

J Ramírez‐Prada, JS Rocha‐Ortiz… - Archiv der …, 2024 - Wiley Online Library
New pyridine‐based chalcones 4a–h and pyrazolines 5a–h (N‐acetyl), 6a–h (N‐phenyl),
and 7a–h (N‐4‐chlorophenyl) were synthesized and evaluated by the National Cancer …

Novel heterocyclic coumarin annulates: synthesis and figuring their roles in biomedicine, bench-to-bedside investigation

NM Zeki, YF Mustafa - Chemical Papers, 2024 - Springer
This study revealed the first synthesis of seven novel coumarins annulated with heterocycle
composed of four heteroatoms, one sulfur, and three oxygen atoms in a linear pattern. This …

Synthesis, In vivo, and In silico Evaluation of New Pyrazoline‐Benzothiazole Conjugates as Antiepileptic Agents

H Singh, R Kumar, A Mazumder… - Chemistry & …, 2024 - Wiley Online Library
Abstract New 2‐(4‐benzothiazol‐2‐yl‐phenoxy)‐1‐(3, 5‐diphenyl‐4, 5‐dihydro‐pyrazol‐1‐
yl)‐ethanones (9a–o) have been designed and synthesized. All the synthesized compounds …

[PDF][PDF] СИНТЕЗ ПЯТИ-И ШЕСТИЧЛЕННЫХ N-СОДЕРЖАЩИХ ГЕТЕРОЦИКЛОВ С ФРАГМЕНТАМИ ЗАМЕЩЕННОГО ФЕНОЛА

ОВ Примерова - gubkin.ru
Актуальность. Пространственно-затрудненные фенолы играют важную роль в
ингибировании свободно-радикального окисления, которое приводит к порче продуктов …