Phospholipid Supply for Autophagosome Biogenesis
D Isola, Z Elazar - Journal of Molecular Biology, 2024 - Elsevier
Autophagy is a cellular degradation pathway where double-membrane autophagosomes
form de novo to engulf cytoplasmic material destined for lysosomal degradation. This …
form de novo to engulf cytoplasmic material destined for lysosomal degradation. This …
No energy, no autophagy—Mechanisms and therapeutic implications of autophagic response energy requirements
M Mandic, V Paunovic, L Vucicevic… - Journal of Cellular …, 2024 - Wiley Online Library
Autophagy is a lysosome‐mediated self‐degradation process of central importance for
cellular quality control. It also provides macromolecule building blocks and substrates for …
cellular quality control. It also provides macromolecule building blocks and substrates for …
Ubiquitin-mediated recruitment of the ATG9A-ATG2 lipid transfer complex drives clearance of phosphorylated p62 aggregates
Autophagy is an essential cellular recycling process that maintains protein and organelle
homeostasis. ATG9A vesicle recruitment is a critical early step in autophagy to initiate …
homeostasis. ATG9A vesicle recruitment is a critical early step in autophagy to initiate …
[HTML][HTML] Non-apoptotic cell death in osteoarthritis: Recent advances and future
P Ji, Z Zhou, J Zhang, T Bai, C Li, B Zhou… - Biomedicine & …, 2024 - Elsevier
Osteoarthritis (OA) is the most common degenerative joint disease. Multiple tissues are
altered during the development of OA, resulting in joint pain and permanent damage to the …
altered during the development of OA, resulting in joint pain and permanent damage to the …
Combined Administration of Metformin and Amprolium to Rats Affects Metabolism of Free Amino Acids in the Brain, Altering Behavior, and Heart Rate
AV Graf, AV Artiukhov, ON Solovjeva… - Biochemistry …, 2024 - Springer
The risk of developing diabetes and cardiometabolic disorders is associated with increased
levels of alpha-aminoadipic acid and disturbances in the metabolism of branched-chain …
levels of alpha-aminoadipic acid and disturbances in the metabolism of branched-chain …
The formation of ubiquitin rich condensates triggers recruitment of the ATG9A lipid transfer complex to initiate basal autophagy
DG Broadbent, CM McEwan, TM Tsang, DM Poole… - Biorxiv, 2023 - pmc.ncbi.nlm.nih.gov
Autophagy is an essential cellular recycling process that maintains protein and organelle
homeostasis. ATG9A vesicle recruitment is a critical early step in autophagy to initiate …
homeostasis. ATG9A vesicle recruitment is a critical early step in autophagy to initiate …