The brain's action-mode network

NUF Dosenbach, ME Raichle… - Nature Reviews …, 2025 - nature.com
The brain is always intrinsically active, using energy at high rates while cycling through
global functional modes. Awake brain modes are tied to corresponding behavioural states …

Adolescent maturation of dorsolateral prefrontal cortex glutamate: GABA and cognitive function is supported by dopamine-related neurobiology

AC Parr, MI Perica, FJ Calabro, W Foran… - Molecular …, 2024 - nature.com
Developmental changes in prefrontal cortex (PFC) excitatory (glutamatergic, Glu) and
inhibitory (gamma-aminobutryic acid, GABA) neurotransmitter balance (E: I) have been …

[HTML][HTML] Functional structure of local connections and differentiation of cerebral cortex areas in the neonate

J Pujol, L Blanco-Hinojo, C Persavento… - NeuroImage, 2024 - Elsevier
Neuroimaging research on functional connectivity can provide valuable information on the
developmental differentiation of the infant cerebral cortex into its functional areas. We …

Shaping dynamical neural computations using spatiotemporal constraints

JZ Kim, B Larsen, L Parkes - Biochemical and Biophysical Research …, 2024 - Elsevier
Dynamics play a critical role in computation. The principled evolution of states over time
enables both biological and artificial networks to represent and integrate information to …

Learning Evolution via Optimization Knowledge Adaptation

C Wang, L Jiao, J Zhao, L Li, F Liu, S Yang - arXiv preprint arXiv …, 2025 - arxiv.org
Evolutionary algorithms (EAs) maintain populations through evolutionary operators to
discover diverse solutions for complex tasks while gathering valuable knowledge, such as …

Pharmacological manipulation of neurotransmitter activity induces disparate effects on cerebral blood flow and resting-state fluctuations

F Munsch, M Taso, DH Wolf, D Press, S Buss… - Imaging …, 2024 - direct.mit.edu
Functional MRI methods can assess aspects of drug-induced brain response. Resting blood
oxygenation level dependent (BOLD) fMRI and arterial spin labeling (ASL) perfusion MRI …

Local activity alterations in autism spectrum disorder correlate with neurotransmitter properties and ketamine induced brain changes

P Grumbach, J Kasper, JF Hipp, A Forsyth, SL Valk… - medRxiv, 2024 - medrxiv.org
Autism spectrum disorder (ASD) is a neurodevelopmental condition associated with altered
resting-state brain function. An increased excitation-inhibition (E/I) ratio is discussed as a …

A sensorimotor-association axis of thalamocortical connection development

VJ Sydnor, J Bagautdinova, B Larsen, MJ Arcaro… - …, 2024 - pmc.ncbi.nlm.nih.gov
Human cortical development follows a sensorimotor-to-association sequence during
childhood and adolescence1–6. The brain's capacity to enact this sequence over decades …

Adolescent maturation of cortical excitation-inhibition balance based on individualized biophysical network modeling

A Saberi, KJ Wischnewski, K Jung, LD Lotter… - …, 2024 - pmc.ncbi.nlm.nih.gov
The balance of excitation and inhibition is a key functional property of cortical microcircuits
which changes through the lifespan. Adolescence is considered a crucial period for the …

[HTML][HTML] Assessing neurocognitive maturation in early adolescence based on baby and adult functional brain landscapes

O Kardan, N Jones, MD Wheelock, C Michael… - …, 2024 - pmc.ncbi.nlm.nih.gov
Adolescence is a period of growth in cognitive performance and functioning. Recently, data-
driven measures of brain-age gap, which can index cognitive decline in older populations …