Perfusion magnetic resonance imaging: a comprehensive update on principles and techniques

GH Jahng, KL Li, L Ostergaard… - Korean journal of …, 2014 - synapse.koreamed.org
Perfusion is a fundamental biological function that refers to the delivery of oxygen and
nutrients to tissue by means of blood flow. Perfusion MRI is sensitive to microvasculature …

Arterial input function in perfusion MRI: a comprehensive review

F Calamante - Progress in nuclear magnetic resonance spectroscopy, 2013 - Elsevier
Cerebral perfusion, also referred to as cerebral blood flow (CBF), is one of the most
important parameters related to brain physiology and function. The technique of dynamic …

Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium

G Seano, HT Nia, KE Emblem, M Datta, J Ren… - Nature biomedical …, 2019 - nature.com
The compression of brain tissue by a tumour mass is believed to be a major cause of the
clinical symptoms seen in patients with brain cancer. However, the biological consequences …

Increased survival of glioblastoma patients who respond to antiangiogenic therapy with elevated blood perfusion

AG Sorensen, KE Emblem, P Polaskova, D Jennings… - Cancer research, 2012 - AACR
The abnormal vasculature of the tumor microenvironment supports progression and
resistance to treatment. Judicious application of antiangiogenic therapy may normalize the …

Vessel architectural imaging identifies cancer patient responders to anti-angiogenic therapy

KE Emblem, K Mouridsen, A Bjornerud, CT Farrar… - Nature medicine, 2013 - nature.com
Measurement of vessel caliber by magnetic resonance imaging (MRI) is a valuable
technique for in vivo monitoring of hemodynamic status and vascular development …

Principles of T2*‐weighted dynamic susceptibility contrast MRI technique in brain tumor imaging

MS Shiroishi, G Castellazzi… - Journal of magnetic …, 2015 - Wiley Online Library
Dynamic susceptibility contrast magnetic resonance imaging (DSC‐MRI) is used to track the
first pass of an exogenous, paramagnetic, nondiffusible contrast agent through brain tissue …

The 39 steps: evading error and deciphering the secrets for accurate dynamic susceptibility contrast MRI

L Willats, F Calamante - NMR in Biomedicine, 2013 - Wiley Online Library
Dynamic susceptibility contrast (DSC) MRI is the most commonly used MRI method to
assess cerebral perfusion and other related haemodynamic parameters. Although the …

Radiophysiomics: brain tumors classification by machine learning and physiological MRI data

A Stadlbauer, F Marhold, S Oberndorfer, G Heinz… - Cancers, 2022 - mdpi.com
Simple Summary The pretreatment diagnosis of contrast-enhancing brain tumors is still
challenging in clinical neuro-oncology due to their very similar appearance on conventional …

Fully-automated deep learning-powered system for DCE-MRI analysis of brain tumors

J Nalepa, PR Lorenzo, M Marcinkiewicz… - Artificial intelligence in …, 2020 - Elsevier
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) plays an important
role in diagnosis and grading of brain tumors. Although manual DCE biomarker extraction …

T1- and T*2-Dominant Extravasation Correction in DSC-MRI: Part I—Theoretical Considerations and Implications for Assessment of Tumor Hemodynamic Properties

A Bjornerud, AG Sorensen… - Journal of Cerebral …, 2011 - journals.sagepub.com
We present a novel contrast agent (CA) extravasation-correction method based on analysis
of the tissue residue function for assessment of multiple hemodynamic parameters. The …