Breast cancer is a highly prevalent disease, accounting for 29% of invasive cancers in
women. Survival from this disease depends on the stage at diagnosis, with patients who are …

The tumor microenvironment is one of the important drivers of tumor development. Cancer-
associated fibroblasts (CAFs) are a major component of the tumor stroma and actively …

Breast cancer is one of the most common cancers with greater than 1,300,000 cases and
450,000 deaths each year worldwide. The development of breast cancer involves a …

During the last decade, gene expression profiling of breast cancer has revealed the
existence of five molecular subtypes and allowed the establishment of a new classification …

Previously, we showed that caveolin-1 (Cav-1) expression is down-regulated in human
breast cancer-associated fibroblasts. However, it remains unknown whether loss of Cav-1 …

Gene expression signatures for a basal-like breast cancer (BLBC) subtype have been
associated with poor clinical outcomes, but a molecular basis for this disease remains …

The specific role of dietary fat in breast cancer progression is unclear, although a low-fat diet
was associated with decreased recurrence of estrogen receptor alpha negative (ER−) breast …

Recent advances in the study of microRNAs indicate that they have an important role in
regulating cellular activities such as proliferation, morphogenesis, apoptosis and …

Caveolin-1 has been linked to tumor progression and clinical outcome in breast cancer, but
a clear resolution of its role as a prognostic marker is lacking. We assessed caveolin-1 …

Background & Objectives: Chromatin structure is the single most important feature that
distinguishes a cancer cell from a normal cell histologically. Chromatin remodeling proteins …