SARS-CoV-2-specific T cells in the changing landscape of the COVID-19 pandemic
Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, multiple severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with increasing ability to …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with increasing ability to …
Exploring the expanding universe of host-virus interactions mediated by viral RNA
RNA is a central molecule in RNA virus biology; however, the interactions that it establishes
with the host cell are only starting to be elucidated. In recent years, a methodology revolution …
with the host cell are only starting to be elucidated. In recent years, a methodology revolution …
SARS-CoV-2 infection of human iPSC–derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19
Although coronavirus disease 2019 (COVID-19) causes cardiac dysfunction in up to 25% of
patients, its pathogenesis remains unclear. Exposure of human induced pluripotent stem cell …
patients, its pathogenesis remains unclear. Exposure of human induced pluripotent stem cell …
Antiviral responses are shaped by heterogeneity in viral replication dynamics
Antiviral signalling, which can be activated in host cells upon virus infection, restricts virus
replication and communicates infection status to neighbouring cells. The antiviral response …
replication and communicates infection status to neighbouring cells. The antiviral response …
Blockage of VEGF function by bevacizumab alleviates early-stage cerebrovascular dysfunction and improves cognitive function in a mouse model of Alzheimer's …
M Zhang, Z Zhang, H Li, Y Xia, M Xing, C Xiao… - Translational …, 2024 - Springer
Background Alzheimer's disease (AD) is a neurodegenerative disorder and the predominant
type of dementia worldwide. It is characterized by the progressive and irreversible decline of …
type of dementia worldwide. It is characterized by the progressive and irreversible decline of …
Mechanosensitive extrusion of Enterovirus A71-infected cells from colonic organoids
J Moshiri, AR Craven, SB Mixon, MR Amieva… - Nature …, 2023 - nature.com
Enterovirus A71 causes severe disease upon systemic infection, sometimes leading to life-
threatening neurological dysfunction. However, in most cases infection is asymptomatic and …
threatening neurological dysfunction. However, in most cases infection is asymptomatic and …
Arabidopsis eIF4E1 protects the translational machinery during TuMV infection and restricts virus accumulation
D Zafirov, N Giovinazzo, C Lecampion, B Field… - PLoS …, 2023 - journals.plos.org
Successful subversion of translation initiation factors eIF4E determines the infection success
of potyviruses, the largest group of viruses affecting plants. In the natural variability of many …
of potyviruses, the largest group of viruses affecting plants. In the natural variability of many …
Cellular fate of a plant virus immunotherapy candidate
Cowpea mosaic virus (CPMV) is a plant virus that is currently being developed for
intratumoral immunotherapy. CPMV relieves the immune system from tumor-induced …
intratumoral immunotherapy. CPMV relieves the immune system from tumor-induced …
In Situ Self‐Assembly of Fluorogenic RNA Nanozipper Enables Real‐Time Imaging of Single Viral mRNA Translation
YP Zhang, ZG Wang, YF Tian, LH Jiang… - Angewandte Chemie …, 2023 - Wiley Online Library
Real‐time visualization of individual viral mRNA translation activities in live cells is essential
to obtain critical details of viral mRNA dynamics and to detect its transient responses to …
to obtain critical details of viral mRNA dynamics and to detect its transient responses to …
Overcoming biological barriers by virus-like drug particles for drug delivery
YL Chen, CJ Bao, JL Duan, Y Xie, WL Lu - Advanced Drug Delivery …, 2023 - Elsevier
Virus-like particles (VLPs) have natural structural antigens similar to those found in viruses,
making them valuable in vaccine immunization. Furthermore, VLPs have demonstrated …
making them valuable in vaccine immunization. Furthermore, VLPs have demonstrated …