Abstract Systems theory has long been used in psychology, biology, and sociology. This
paper applies newer methods of control systems modeling for assessing system stability in …

The stress-activated signaling pathways, p53 and NF-κB, have a major role in the regulation
of cellular senescence and organismal aging. These ancient signaling networks display …

Examining enzyme kinetics is critical for understanding cellular systems and for using
enzymes in industry. The Michaelis-Menten equation has been widely used for over a …

Intrinsically photosensitive retinal ganglion cells (ipRGC) signal environmental light level to
the central circadian clock and contribute to the pupil light reflex. It is unknown if ipRGC …

Gene expression in mammalian cells is highly variable and episodic, resulting in a series of
discontinuous bursts of mRNAs. A challenge is to understand how static promoter …

The cell biology of circadian clocks is still in its infancy. Here, we describe an efficient
strategy for generating knock-in reporter cell lines using CRISPR technology that is …

To understand differences in host-Candida albicans interactions that occur during
colonization of healthy or compromised hosts, production of phenotypic variants and …

We experimentally demonstrate group synchrony in a network of four nonlinear
optoelectronic oscillators with time-delayed coupling. We divide the nodes into two groups of …

Spontaneous molecular oscillations are ubiquitous in biology. But to our knowledge,
periodic cell migratory patterns have not been observed. Here we report the highly regular …

Motivation Time courses utilizing genome scale data are a common approach to identifying
the biological pathways that are controlled by the circadian clock, an important regulator of …