The potential of metabolomics in biomedical applications

V Gonzalez-Covarrubias, E Martínez-Martínez… - Metabolites, 2022 - mdpi.com
The metabolome offers a dynamic, comprehensive, and precise picture of the phenotype.
Current high-throughput technologies have allowed the discovery of relevant metabolites …

Ion mobility mass spectrometry in the omics era: Challenges and opportunities for metabolomics and lipidomics

G Paglia, AJ Smith, G Astarita - Mass spectrometry reviews, 2022 - Wiley Online Library
Researchers worldwide are taking advantage of novel, commercially available,
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …

[HTML][HTML] Supercritical fluid chromatography–Mass spectrometry in metabolomics: Past, present, and future perspectives

B van de Velde, D Guillarme, I Kohler - Journal of Chromatography B, 2020 - Elsevier
Metabolomics, which consists of the comprehensive analysis of metabolites within a
biological system, has been playing a growing role in the implementation of personalized …

Current state and future perspectives of supercritical fluid chromatography

L Si-Hung, T Bamba - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
For quite of time, supercritical fluid chromatography (SFC) is expected to make a big
revolution in separation technologies. The technique is well known for developing fast and …

[HTML][HTML] Metamorphosis of supercritical fluid chromatography: a viable tool for the analysis of polar compounds?

GL Losacco, JL Veuthey, D Guillarme - TrAC Trends in Analytical …, 2021 - Elsevier
Recent developments in supercritical fluid chromatography (SFC) have highlighted the
applicability of this technique for the analysis of highly polar compounds. The combination of …

[图书][B] Liquid chromatography: applications

S Fanali, PR Haddad, C Poole, ML Riekkola - 2017 - books.google.com
Liquid Chromatography: Applications, Second Edition, is a single source of authoritative
information on all aspects of the practice of modern liquid chromatography. It gives those …

Approaches in metabolomics for regulatory toxicology applications

E Olesti, V González-Ruiz, MF Wilks, J Boccard… - Analyst, 2021 - pubs.rsc.org
Innovative methodological approaches are needed to conduct human health and
environmental risk assessments on a growing number of marketed chemicals. Metabolomics …

Chromatographic analysis of biomolecules with pressurized carbon dioxide mobile phases–A review

J Molineau, M Hideux, C West - Journal of Pharmaceutical and Biomedical …, 2021 - Elsevier
Biomolecules like proteins, peptides and nucleic acids widely emerge in pharmaceutical
applications, either as synthetic active pharmaceutical ingredients, or from natural products …

[HTML][HTML] Expanding the range of sub/supercritical fluid chromatography: advantageous use of methanesulfonic acid in water-rich modifiers for peptide analysis

GL Losacco, JO DaSilva, J Liu, EL Regalado… - … of Chromatography A, 2021 - Elsevier
The aim of this work was to expand the applicability range of UHPSFC to series of synthetic
and commercialized peptides. Initially, a screening of different column chemistries available …

Analysis of short-chain bioactive peptides by unified chromatography-electrospray ionization mass spectrometry. Part I. Method development

J Molineau, Y Hamel, M Hideux, P Hennig… - … of Chromatography A, 2021 - Elsevier
A method to analyse short-chain bioactive peptides (MW< 800 Da) and their impurities was
developed with a unified chromatography (UC) analysis, including a wide mobile phase …