Low-density lipoprotein cholesterol levels are associated with poor clinical outcomes in COVID-19

Á Aparisi, C Iglesias-Echeverría… - Nutrition, Metabolism …, 2021 - Elsevier
Background and aims Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
the sole causative agent of coronavirus infectious disease-19 (COVID-19). Methods and …

Relationship between lipoprotein concentrations and short-term and 1-year mortality in intensive care unit septic patients: results from the HIGHSEPS study

S Tanaka, J Stern, D Bouzid, T Robert, M Dehoux… - Annals of Intensive …, 2021 - Springer
Abstract Background High-density lipoproteins (HDLs), particles characterized by their
reverse cholesterol transport function, display pleiotropic properties, including anti …

U-shaped association between serum triglyceride levels and mortality among septic patients: An analysis based on the MIMIC-IV database

M Xiao, H Deng, W Mao, Y Liu, Q Yang, Y Liu, J Fan… - Plos one, 2023 - journals.plos.org
Background Sepsis is characterized by upregulated lipolysis in adipose tissue and a high
blood triglyceride (TG) level. It is still debated whether serum TG level is related to mortality …

[PDF][PDF] 脓毒症患者血脂与炎症因子水平的相关性研究

徐亚楠, 王栋, 刘欢, 丁显飞, 张晓娟, 刘韶华… - 中华危重病急救 …, 2022 - cccm-em120.com
目的探讨脓毒症患者血脂水平与炎症反应强度及病情严重程度的关系, 以期寻找一种可以快速
评估脓毒症病情及预后的生物标志物. 方法回顾性选择2019 年10 月至2021 年5 …

[HTML][HTML] Causal relationships between plasma lipids and sepsis: a Mendelian randomization study

J Chen, W Chen, L Wu, RH Wang, JJ Xiang, FK Zheng… - Medicine, 2023 - journals.lww.com
Although observational studies have indicated that plasma lipids are associated with an
increased risk of sepsis, due to confounders and reverse causality, the causal relationship …

Increased phospholipid transfer protein activity is associated with markers of enhanced lipopolysaccharide clearance in human during cardiopulmonary bypass

M Nguyen, T Gautier, G Reocreux, G Pallot… - Frontiers in …, 2021 - frontiersin.org
Introduction: Lipopolysaccharide (LPS) is a component of gram-negative bacteria, known for
its ability to trigger inflammation. The main pathway of LPS clearance is the reverse …

A prospective cohort study of severe sepsis-induced dyslipidemia and changes in D-dimer levels in children: do they affect the prognosis?

TA Abdelaziz, MAA Mohamed, WI Ismail… - Egyptian Pediatric …, 2023 - Springer
Background The dyslipidemia and changes in D-dimer values that occur in children with
severe sepsis remain unidentified. Objective The current research aimed to explore the …

Mendelian Randomization Analysis Identifies Causal Associations Between Serum Lipidomic Profile, Amino Acid Biomarkers and Sepsis

Z Zhu, J Ma, D Ji, Q Li, X Diao, J Bao - Heliyon, 2024 - cell.com
Background Sepsis is a life-threatening condition marked by a severe systemic response to
infection, leading to widespread inflammation, cellular signaling disruption, and metabolic …

[HTML][HTML] High cholesterol concentrations as well as low cholesterol concentrations are associated with mortality at 28 days in sepsis: a retrospective cohort study

DH Jang, YH Jo, GJ Suh, WY Kwon… - Annals of palliative …, 2021 - apm.amegroups.org
Background: Low serum cholesterol is known to be associated with poor prognosis in sepsis
patients. On the other hand, there have been few studies on the association between high …

[HTML][HTML] Predictive value of laboratory indicators for in-hospital death in children with community-onset sepsis: a prospective observational study of 266 patients

Q Hui, X Lu, W Li, N Li, Y Chen, Q Zhang - BMJ Paediatrics Open, 2024 - ncbi.nlm.nih.gov
Methods Children with sepsis were enrolled consecutively in a prospective observational
study involving paediatric intensive care units (PICUs) of two hospitals in Beijing, between …