CRISPR/Cas and argonaute-based biosensors for pathogen detection
Z Yang, S Mao, L Wang, S Fu, Y Dong… - ACS …, 2023 - ACS Publications
Over the past few decades, pathogens have posed a threat to human security, and rapid
identification of pathogens should be one of the ideal methods to prevent major public …
identification of pathogens should be one of the ideal methods to prevent major public …
Next-generation CRISPR-based diagnostic tools for human diseases
Accurate diagnosis of human diseases is crucial for effective prevention, clinical treatment,
and prognosis. The World Health Organization (WHO) has provided guidelines for molecular …
and prognosis. The World Health Organization (WHO) has provided guidelines for molecular …
Argonaute-DNAzyme tandem biosensing for highly sensitive and simultaneous dual-gene detection of methicillin-resistant Staphylococcus aureus
Y Li, X Tang, N Wang, Z Zhao, S Man, L Zhu… - Biosensors and …, 2024 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA), a common zoonotic multidrug-resistant
bacterium, puts a great threat to public health and food safety. Rapid and reliable detection …
bacterium, puts a great threat to public health and food safety. Rapid and reliable detection …
Recent advances of food safety detection by nucleic acid isothermal amplification integrated with CRISPR/Cas
J Qiao, Z Zhao, Y Li, M Lu, S Man, S Ye… - Critical Reviews in …, 2024 - Taylor & Francis
Food safety problems have become one of the most important public health issues
worldwide. Therefore, the development of rapid, effective and robust detection is of great …
worldwide. Therefore, the development of rapid, effective and robust detection is of great …
CRISPR/Cas-powered amplification-free detection of nucleic acids: current state of the art, challenges, and futuristic perspectives
Y Li, Y Liu, X Tang, J Qiao, J Kou, S Man, L Zhu… - ACS …, 2023 - ACS Publications
CRISPR/Cas system is becoming an increasingly influential technology that has been
repositioned in nucleic acid detection. A preamplification step is usually required to improve …
repositioned in nucleic acid detection. A preamplification step is usually required to improve …
CRISPR-based biosensors for human health: A novel strategy to detect emerging infectious diseases
Infectious diseases (such as sepsis, influenza, and malaria), caused by various pathogenic
bacteria and viruses, are widespread across the world. Early and rapid detection of disease …
bacteria and viruses, are widespread across the world. Early and rapid detection of disease …
CRISPR/Cas13a-Responsive and RNA-Bridged DNA Hydrogel Capillary Sensor for Point-of-Care Detection of RNA
H Wang, H Wang, H Pian, F Su, F Tang… - Analytical …, 2024 - ACS Publications
Disease diagnostics and surveillance increasingly highlight the importance of portable, cost-
effective, and sensitive point-of-care (POC) detection of nucleic acids. Here, we report a …
effective, and sensitive point-of-care (POC) detection of nucleic acids. Here, we report a …
A one-pot method based on rolling circle amplification and light‐activated CRISPR/Cas12a reaction for simple and highly sensitive detection of Staphylococcus …
Q Wu, S Jiang, Y Huang, L Zhang, Z Li, Y Hou… - Chemical Engineering …, 2023 - Elsevier
Developing robust methods that achieve simple and highly sensitive detection of
Staphylococcus aureus (S. aureus) is still a challenge. Isothermal nucleic acid amplification …
Staphylococcus aureus (S. aureus) is still a challenge. Isothermal nucleic acid amplification …
Recent Progress in Molecular Diagnostics: The Synergy of Rolling Circle Amplification and CRISPR/Cas Systems (2018-2024)–A Concise Review
Z Zhu, L Yang - TrAC Trends in Analytical Chemistry, 2024 - Elsevier
Abstract The fusion of Rolling Circle Amplification (RCA) and the Clustered Regularly
Interspaced Short Palindromic Repeats–CRISPR-associated proteins (CRISPR-Cas) stands …
Interspaced Short Palindromic Repeats–CRISPR-associated proteins (CRISPR-Cas) stands …
Multiplex detection of infectious diseases on microfluidic platforms
Infectious diseases contribute significantly to the global disease burden. Sensitive and
accurate screening methods are some of the most effective means of identifying sources of …
accurate screening methods are some of the most effective means of identifying sources of …