Biology and therapeutic targeting of vascular endothelial growth factor A

L Pérez-Gutiérrez, N Ferrara - Nature Reviews Molecular Cell Biology, 2023 - nature.com
The formation of new blood vessels, called angiogenesis, is an essential pathophysiological
process in which several families of regulators have been implicated. Among these, vascular …

Angiogenic signaling pathways and anti-angiogenic therapy for cancer

ZL Liu, HH Chen, LL Zheng, LP Sun… - Signal transduction and …, 2023 - nature.com
Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …

Multiple stimuli‐responsive nanozyme‐based cryogels with controlled NO release as self‐adaptive wound dressing for infected wound healing

Y Yang, M Li, G Pan, J Chen… - Advanced Functional …, 2023 - Wiley Online Library
Wound with drug‐resistant bacterial infections has become a serious challenge for the
healthcare system, and designing wound dressing to self‐adapt to the need of different …

A stretchable wireless wearable bioelectronic system for multiplexed monitoring and combination treatment of infected chronic wounds

E Shirzaei Sani, C Xu, C Wang, Y Song, J Min, J Tu… - Science …, 2023 - science.org
Chronic nonhealing wounds are one of the major and rapidly growing clinical complications
all over the world. Current therapies frequently require emergent surgical interventions …

The biological applications of DNA nanomaterials: current challenges and future directions

W Ma, Y Zhan, Y Zhang, C Mao, X Xie… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

Accelerated skin wound healing by electrical stimulation

R Luo, J Dai, J Zhang, Z Li - Advanced healthcare materials, 2021 - Wiley Online Library
When the integrity of the skin got damaged, an endogenous electric field will be generated
in the wound and a series of physiological reactions will be initiated to close the wound. The …

Macrophages and the maintenance of homeostasis

DM Mosser, K Hamidzadeh, R Goncalves - Cellular & molecular …, 2021 - nature.com
There have been many chapters written about macrophage polarization. These chapters
generally focus on the role of macrophages in orchestrating immune responses by …

Biodegradable and Electroactive Regenerated Bacterial Cellulose/MXene (Ti3C2Tx) Composite Hydrogel as Wound Dressing for Accelerating Skin Wound …

L Mao, S Hu, Y Gao, L Wang, W Zhao… - Advanced …, 2020 - Wiley Online Library
Traditional wound dressings mainly participate in the passive healing processes and are
rarely engaged in active wound healing by stimulating skin cell behaviors. Electrical …

Scaffolds for wound healing applications

I Negut, G Dorcioman, V Grumezescu - Polymers, 2020 - mdpi.com
In order to overcome the shortcomings related to unspecific and partially efficient
conventional wound dressings, impressive efforts are oriented in the development and …

Biomaterials: foreign bodies or tuners for the immune response?

E Mariani, G Lisignoli, RM Borzì… - International journal of …, 2019 - mdpi.com
The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …