From imbalance to impairment: the central role of reactive oxygen species in oxidative stress-induced disorders and therapeutic exploration

S Afzal, AS Abdul Manap, A Attiq… - Frontiers in …, 2023 - frontiersin.org
Increased production and buildup of reactive oxygen species (ROS) can lead to various
health issues, including metabolic problems, cancers, and neurological conditions. Our …

Clinical parameters and epigenetic biomarkers of plaque vulnerability in patients with carotid stenosis

L Carballo-Perich, D Puigoriol-Illamola… - International Journal of …, 2022 - mdpi.com
Atheromatous disease is the first cause of death and dependency in developed countries
and carotid artery atherosclerosis is one of the main causes of severe ischaemic strokes …

Anti-inflammatory activity of geraniol isolated from lemon grass on Ox-LDL-stimulated endothelial cells by upregulation of Heme Oxygenase-1 via PI3K/Akt and Nrf-2 …

R Ben Ammar, ME Mohamed, M Alfwuaires… - Nutrients, 2022 - mdpi.com
Among the world's leading causes of cardiovascular disease, atherosclerosis is a chronic
inflammatory disorder that affects the arteries. Both vasodilation and vasoconstriction, low …

Update on biomarkers associated with large-artery atherosclerosis stroke

M Rosário, AC Fonseca - Biomolecules, 2023 - mdpi.com
Intracranial and extracranial large-artery atherosclerosis (LAA) are a main cause of ischemic
stroke. Biomarkers may aid in the diagnosis of LAA and help to stratify patients' risk of stroke …

[HTML][HTML] ALG2 inhibits the epithelial-to-mesenchymal transition and stemness of ovarian granulosa cells through the Wnt/β-catenin signaling pathway in polycystic …

Q Zheng, M Liu, J Fu - Reproductive Biology, 2022 - Elsevier
Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects fertility in women of
reproductive age, and a leading cause of anovulatory infertility. Ovarian granulosa cells are …

Oxidative Stress as a Reliable Biomarker of Carotid Plaque Instability: A Pilot Study

N Svoboda, K Kočí, A Seidlová, V Mandys, J Suttnar… - Antioxidants, 2023 - mdpi.com
Background: Predicting stroke risk in patients with carotid artery stenosis (CS) remains
challenging. Circulating biomarkers seem to provide improvements with respect to risk …

[HTML][HTML] Multiscale optoacoustic assessment of skin microvascular reactivity in carotid artery disease

A Karlas, N Katsouli, NA Fasoula, M Reidl, R Lees… - Photoacoustics, 2024 - Elsevier
Microvascular endothelial dysfunction may provide insights into systemic diseases, such as
carotid artery disease. Raster-scan optoacoustic mesoscopy (RSOM) can produce images of …

Intracranial plaque characteristics on high-resolution MRI and high-sensitivity C-reactive protein levels: association and clinical relevance in acute cerebral infarction

RY Li, DL Zhao, JW Yu, Y Wu, XH Chen, H Ge, C Li… - Clinical Radiology, 2023 - Elsevier
AIM To investigate the association between intracranial plaque characteristics and high-
sensitivity C-reactive protein (hs-CRP) levels, and their combined effects on the occurrence …

Molekulare Biomarker der Atherosklerose

AG Hofmann, CJ Binder - Gefässchirurgie, 2022 - Springer
Zusammenfassung Die Hoffnung, durch im Blut zirkulierende Biomarker Rückschlüsse auf
lokale atherosklerotische Prozesse zu generieren, hat in der Vergangenheit zur Erforschung …

Multimodality Imaging Classification for Carotid Plaque Assessment

TZ Naqvi - Cardiovascular Imaging, 2024 - jacc.org
Multiple imaging studies have shown a high prevalence of carotid atherosclerosis in the
asymptomatic Western population. 1 Clinical practice continues to focus on carotid stenosis …