An evolving scientific basis for the prevention and treatment of pediatric obesity

PT Katzmarzyk, S Barlow, C Bouchard… - International journal of …, 2014 - nature.com
Abstract The 2013 Pennington Biomedical Research Center's Scientific Symposium focused
on the treatment and management of pediatric obesity and was designed to (i) review recent …

Sexual dimorphism in white and brown adipose tissue with obesity and inflammation

ID Bloor, ME Symonds - Hormones and behavior, 2014 - Elsevier
This article is part of a Special Issue “Energy Balance”. Obesity and its associated
comorbidities remain at epidemic levels globally and show no signs of abatement in either …

[HTML][HTML] Excess vitamins or imbalance of folic acid and choline in the gestational diet alter the gut microbiota and obesogenic effects in wistar rat offspring

UN Mjaaseth, JC Norris, NDJ Aardema, ML Bunnell… - Nutrients, 2021 - mdpi.com
Excess vitamin intake during pregnancy leads to obesogenic phenotypes, and folic acid
accounts for many of these effects in male, but not in female, offspring. These outcomes may …

[HTML][HTML] Current knowledge on the pathophysiology of lean/normal-weight type 2 diabetes

T Salvatore, R Galiero, A Caturano, L Rinaldi… - International Journal of …, 2022 - mdpi.com
Since early times, being overweight and obesity have been associated with impaired
glucose metabolism and type 2 diabetes (T2D). Similarly, a less frequent adult-onset …

[HTML][HTML] Fat mass- and obesity-associated gene Fto affects the dietary response in mouse white adipose tissue

J Ronkainen, TJ Huusko, R Soininen, E Mondini… - Scientific reports, 2015 - nature.com
Common variants of human fat mass-and obesity-associated gene Fto have been linked
with higher body mass index, but the biological explanation for the link has remained …

[HTML][HTML] Low temperature exposure induces browning of bone marrow stem cell derived adipocytes in vitro

K Velickovic, HA Lugo Leija, I Bloor, J Law, H Sacks… - Scientific reports, 2018 - nature.com
Brown and beige adipocytes are characterised as expressing the unique mitochondrial
uncoupling protein (UCP) 1 for which the primary stimulus in vivo is cold exposure. The …

Invited review: Evolution of meat animal growth research during the past 50 years: Adipose and muscle stem cells

MV Dodson, RE Allen, M Du, WG Bergen… - Journal of animal …, 2015 - academic.oup.com
If one were to compare today's animal growth research to research from a mere 50 yr ago,
one would see programs with few similarities. The evolution of this research from whole …

Maternal health and eating habits: metabolic consequences and impact on child health

S Ojha, HP Fainberg, S Sebert, H Budge… - Trends in molecular …, 2015 - cell.com
Apart from direct inheritance and the effects of a shared environment, maternal health,
eating habits and diet can affect offspring health by developmental programming …

Adipose depots differ in cellularity, adipokines produced, gene expression, and cell systems

MV Dodson, M Du, S Wang, WG Bergen… - Adipocyte, 2014 - Taylor & Francis
The race to manage the health concerns related to excess fat deposition has spawned a
proliferation of clinical and basic research efforts to understand variables including dietary …

[HTML][HTML] RNA-seq characterization of sex-differences in adipose tissue of obesity affected patients: computational analysis of differentially expressed coding and non …

F Rey, L Messa, C Pandini, E Maghraby… - Journal of personalized …, 2021 - mdpi.com
Obesity is a multifactorial disease presenting sex-related differences including adipocyte
functions, sex hormone effects, genetics, and metabolic inflammation. These can influence …