Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

Christopher R. Holroyd1, Rakhi Seth1, Marwan Bukhari2, Anshuman Malaviya3, Claire
Holmes1, Elizabeth Curtis4, Christopher Chan1, Mohammed A. Yusuf3, Anna Litwic4, 5 …

Guidelines for clinical practice are intended to suggest preferable approaches to particular
medical problems as established by interpretation and collation of scientifically valid …

Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, are
lifelong conditions that often begin in childhood. The implications of IBD are of particular …

Background and aims: This study evaluates the long-term safety of infliximab in patients with
inflammatory bowel disease (IBD) treated with the drug over a 14-year period. Methods: The …

The disorders collectively known as inflammatory bowel disease (IBD) include Crohn's
disease (CD) and ulcerative colitis (UC). CD, initially credited as having been described in …

In view of the increased risk of TB reactivation with anti-TNF alpha treatment, various
professional groups have sought the advice of the Joint Tuberculosis Committee of the …

In the last decade, biologic agents, in particular anti-TNF agents such as infliximab,
adalimumab, and certolizumab have substantially extended the therapeutic armamentarium …

Objective: To analyse the performance of a new M tuberculosis-specific interferon γ (IFNγ)
assay in patients with chronic inflammatory diseases who receive immunosuppressive …

Worldwide, over 400 000 patients have been treated with tumour necrosis factor (TNF)-α
antagonists for indications that include rheumatoid arthritis, juvenile rheumatoid arthritis …