One in 4 Americans> 40 years of age takes a statin to reduce the risk of myocardial
infarction, ischemic stroke, and other complications of atherosclerotic disease. The most …

Abstract Treatment with statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A
reductase, has proven beneficial preventive effects on cardiovascular events. However …

Moreover, over the last few years the approach to treatment of patients with a high
cardiovascular risk has totally changed from treatment aimed at a specific risk factor (ie …

Aims To objectively appraise evidence for possible adverse effects of long-term statin
therapy on glucose homeostasis, cognitive, renal and hepatic function, and risk for …

Statins are one of the most commonly prescribed drugs in clinical practice. They are usually
well tolerated and effectively prevent cardiovascular events. Most adverse effects associated …

The 2019 novel coronavirus, known as severe acute respiratory syndrome-coronavirus 2
(SARS-CoV-2) or coronavirus disease 2019 (COVID-19), is causing a global pandemic. The …

Vascular calcification is a strong independent predictor of increased cardiovascular
morbidity and mortality and has a high prevalence among patients with chronic kidney …

The presence of residual cardiovascular disease (CVD) risk is a current dilemma in clinical
practice; indeed, despite optimal management and treatment, a considerable proportion of …

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD)
worldwide. Its pathogenesis encompasses functional alterations involving elevated …

Background The effects of statins in patients with diabetic nephropathy are controversial.
With increasing interest in the potential therapeutic role of statins in diabetic nephropathy, it …