Multifunctional smart hydrogels: Potential in tissue engineering and cancer therapy

X Li, X Su - Journal of Materials Chemistry B, 2018 - pubs.rsc.org
In recent years, clinical applications have been proposed for various hydrogel products.
Hydrogels can be derived from animal tissues, plant extracts and/or adipose tissue …

Prodigiosin: A promising biomolecule with many potential biomedical applications

GA Islan, B Rodenak-Kladniew, N Noacco… - …, 2022 - Taylor & Francis
Pigments are among the most fascinating molecules found in nature and used by human
civilizations since the prehistoric ages. Although most of the bio-dyes reported in the …

[HTML][HTML] Anomalous release kinetics of prodigiosin from poly-N-isopropyl-acrylamid based hydrogels for the treatment of triple negative breast cancer

Y Danyuo, CJ Ani, AA Salifu, JD Obayemi… - Scientific reports, 2019 - nature.com
This paper presents the anomalous release kinetics of a cancer drug (prodigiosin) frompoly-
n-isopropyl-acrylamide (P (NIPA))-based gels. The release exponents, n, which correspond …

Degradable porous drug-loaded polymer scaffolds for localized cancer drug delivery and breast cell/tissue growth

JD Obayemi, SM Jusu, AA Salifu, S Ghahremani… - Materials Science and …, 2020 - Elsevier
This paper presents the results of a combined experimental and analytical study of blended
FDA-approved polymers [polylactic-co-glycolic acid (PLGA), polyethylene glycol (PEG) and …

Recent advances in novel drug delivery systems and approaches for management of breast cancer: A comprehensive review

U Hani, M Rahamathulla, RA Osmani, HY Kumar… - Journal of Drug Delivery …, 2020 - Elsevier
Breast Cancer (BC) is a carcinoma of breast tissues, the major recurrent cancer in women
and also the foremost cause of death with approximate 5 million annual deaths worldwide …

Extraction and encapsulation of prodigiosin in chitosan microspheres for targeted drug delivery

SO Dozie-Nwachukwu, Y Danyuo, JD Obayemi… - Materials Science and …, 2017 - Elsevier
The encapsulation of drugs in polymeric materials has brought opportunities to the targeted
delivery of chemotherapeutic agents. These polymeric delivery systems are capable of …

[HTML][HTML] Synthesis and characterization of chitosan/polyvinyl alcohol crosslinked poly (N-isopropylacrylamide) smart hydrogels via γ-radiation

DR Barleany, AS Utama, U Riyupi, H Alwan… - Materials Today …, 2023 - Elsevier
Chitosan-based smart hydrogels with stable mechanics and good flexibility have many
desirable qualities and broad applications. In this study, novel smart hydrogels of chitosan …

PLGA-based microparticles loaded with bacterial-synthesized prodigiosin for anticancer drug release: Effects of particle size on drug release kinetics and cell viability

JD Obayemi, Y Danyuo, S Dozie-Nwachukwu… - Materials Science and …, 2016 - Elsevier
This paper presents the synthesis and physicochemical characterization of biodegradable
poly (d, l-lactide-co-glycolide)(PLGA)-based microparticles that are loaded with bacterial …

NIR-responsive ROS generating core and ROS-triggered 5′-Deoxy-5-fluorocytidine releasing shell structured water-swelling microgel for locoregional combination …

J Lee, R Jenjob, E Davaa, SG Yang - Journal of Controlled Release, 2019 - Elsevier
Combination chemotherapy now becomes the most standard cancer treatment protocol.
Here, we present a core-shell type polymeric microgel (CSPM) which combines …

[HTML][HTML] In-vivo studies of targeted and localized cancer drug release from microporous poly-di-methyl-siloxane (PDMS) devices for the treatment of triple negative …

SC Eluu, JD Obayemi, AA Salifu, D Yiporo, AO Oko… - Scientific Reports, 2024 - nature.com
Triple-negative breast cancer (TNBC) treatment is challenging and frequently characterized
by an aggressive phenotype and low prognosis in comparison to other subtypes. This paper …