[HTML][HTML] Oxytocin in schizophrenia: pathophysiology and implications for future treatment
Schizophrenia is a form of mental disorder that is behaviorally characterized by abnormal
behavior, such as social function deficits or other behaviors that are disconnected from …
behavior, such as social function deficits or other behaviors that are disconnected from …
The role of oxytocin and vasopressin dysfunction in cognitive impairment and mental disorders
O Abramova, Y Zorkina, V Ushakova, E Zubkov… - Neuropeptides, 2020 - Elsevier
Oxytocin (OXT) and arginine-vasopressin (AVP) are structurally homologous peptide
hormones synthesized in the hypothalamus. Nowadays, the role of OXT and AVP in the …
hormones synthesized in the hypothalamus. Nowadays, the role of OXT and AVP in the …
A review of oxytocin's effects on the positive, negative, and cognitive domains of schizophrenia
D Feifel, PD Shilling, K MacDonald - Biological psychiatry, 2016 - Elsevier
Schizophrenia is a disabling, heterogeneous disorder with clinical features that can be
parsed into three domains: positive symptoms, negative symptoms, and cognitive deficits …
parsed into three domains: positive symptoms, negative symptoms, and cognitive deficits …
Oxytocin effects in schizophrenia: reconciling mixed findings and moving forward
ER Bradley, JD Woolley - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Schizophrenia is a severe mental illness that causes major functional impairment. Current
pharmacologic treatments are inadequate, particularly for addressing negative and cognitive …
pharmacologic treatments are inadequate, particularly for addressing negative and cognitive …
Potential of oxytocin in the treatment of schizophrenia
PD Shilling, D Feifel - CNS drugs, 2016 - Springer
Schizophrenia is a heterogeneous, debilitating disorder characterized by three distinct sets
of clinical features: positive symptoms, negative symptoms, and cognitive deficits. Extant …
of clinical features: positive symptoms, negative symptoms, and cognitive deficits. Extant …
Intranasal oxytocin may improve high-level social cognition in schizophrenia, but not social cognition or neurocognition in general: a multilevel bayesian meta …
While there is growing interest in the potential for intranasal oxytocin (IN-OT) to improve
social cognition and neurocognition (ie, nonsocial cognition) in schizophrenia, the extant …
social cognition and neurocognition (ie, nonsocial cognition) in schizophrenia, the extant …
[HTML][HTML] Crosstalk between schizophrenia and metabolic syndrome: The role of oxytocinergic dysfunction
KK Goh, CYA Chen, TH Wu, CH Chen… - International journal of …, 2022 - mdpi.com
The high prevalence of metabolic syndrome in persons with schizophrenia has spurred
investigational efforts to study the mechanism beneath its pathophysiology. Early psychosis …
investigational efforts to study the mechanism beneath its pathophysiology. Early psychosis …
[HTML][HTML] Progress and pitfalls in developing agents to treat neurocognitive deficits associated with schizophrenia
T Veselinović, I Neuner - CNS drugs, 2022 - Springer
Cognitive impairments associated with schizophrenia (CIAS) represent a central element of
the symptomatology of this severe mental disorder. CIAS substantially determine the …
the symptomatology of this severe mental disorder. CIAS substantially determine the …
Endogenous oxytocin levels are associated with impaired social cognition and neurocognition in schizophrenia
GP Strauss, HC Chapman, WR Keller, JI Koenig… - Journal of Psychiatric …, 2019 - Elsevier
Intranasal administration of the neuropeptide oxytocin (OT) has yielded inconsistent effects
on social cognition and general cognition in individuals with schizophrenia (SZ). Few …
on social cognition and general cognition in individuals with schizophrenia (SZ). Few …
Oxytocin and excitation/inhibition balance in social recognition
OL Lopatina, YK Komleva, YV Gorina… - Neuropeptides, 2018 - Elsevier
Social recognition is the sensitive domains of complex behavior critical for identification,
interpretation and storage of socially meaningful information. Social recognition develops …
interpretation and storage of socially meaningful information. Social recognition develops …