Obesity and cancer: a current overview of epidemiology, pathogenesis, outcomes, and management

S Pati, W Irfan, A Jameel, S Ahmed, RK Shahid - Cancers, 2023 - mdpi.com
Simple Summary Obesity has been linked to several common cancers including breast,
colorectal, esophageal, kidney, gallbladder, uterine, pancreatic, and liver cancer. Obesity …

Breast cancer—epidemiology, risk factors, classification, prognostic markers, and current treatment strategies—an updated review

S Łukasiewicz, M Czeczelewski, A Forma, J Baj… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is the most common cancer among women. It is estimated
that 2.3 million new cases of BC are diagnosed globally each year. Based on mRNA gene …

The associations between modifiable risk factors and nonalcoholic fatty liver disease: A comprehensive Mendelian randomization study

J Xie, H Huang, Z Liu, Y Li, C Yu, L Xu, C Xu - Hepatology, 2023 - journals.lww.com
Conclusions: Genetically predicted alcohol frequency, elevated serum liver enzymes, poor
physical condition, obesity traits, T2DM, and hypertension were associated with an …

Obesity, type 2 diabetes, and cancer risk

T Scully, A Ettela, D LeRoith, EJ Gallagher - Frontiers in oncology, 2021 - frontiersin.org
Obesity and type 2 diabetes have both been associated with increased cancer risk and are
becoming increasingly prevalent. Metabolic abnormalities such as insulin resistance and …

Association between regional body fat and cardiovascular disease risk among postmenopausal women with normal body mass index

GC Chen, R Arthur, NM Iyengar… - European heart …, 2019 - academic.oup.com
Aims Central adiposity is associated with increased cardiovascular disease (CVD) risk, even
among people with normal body mass index (BMI). We tested the hypothesis that regional …

Triple-negative breast cancer: a brief review about epidemiology, risk factors, signaling pathways, treatment and role of artificial intelligence

NM Almansour - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is a kind of breast cancer that lacks estrogen,
progesterone, and human epidermal growth factor receptor 2. This cancer is responsible for …

Obesity, metabolic syndrome, and cancer: pathophysiological and therapeutic associations

N Mili, SA Paschou, DG Goulis, MA Dimopoulos… - Endocrine, 2021 - Springer
Overweight, obesity, and metabolic syndrome (MetS) have become epidemic conditions
affecting 39%, 13%, and 20% of the population respectively. The aim of this article is to …

Metabolic dysfunction and obesity‐related cancer: beyond obesity and metabolic syndrome

P Karra, M Winn, S Pauleck, A Bulsiewicz‐Jacobsen… - …, 2022 - Wiley Online Library
Objectives: The metabolic dysfunction driven by obesity, including hyperglycemia and
dyslipidemia, increases risk for developing at least 13 cancer types. The concept of …

Normal weight obesity and unaddressed cardiometabolic health risk—a narrative review

NN Wijayatunga, EJ Dhurandhar - International journal of obesity, 2021 - nature.com
Normal weight obesity (NWO) is defined as having a normal body mass index (BMI), but a
high body fat mass. There is growing interest in individuals with NWO, which is an …

[HTML][HTML] Sarcopenia and mortality in cancer: A meta-analysis

PCM Au, HL Li, GKY Lee, GHY Li, M Chan… - Osteoporosis and …, 2021 - Elsevier
Objectives The aim of this meta-analysis is to comprehensively evaluate the effects of lean
mass on all-cause mortality across different cancer types. Methods This is a meta-analysis …