Antibiotic resistance is a growing public health concern. The quest to understand the
underlying mechanisms of drug resistance needs to be accompanied by an expanded …

Heterocyclic compounds bearing the pyrimidine core are of tremendous interest as they
constitute an important class of natural and synthetic compounds exhibiting diverse useful …

In this study, a new compound namely 1-((2-hydroxynaphthalen-1-yl) methyleneamino)-5-(4-
methybenzoyl)-4-p-tolylpyrimidin-2 (1H)-one (S2) was synthesized as a Schiff base using 1 …

In the present study, Schiff-based Iron (II), Nickel (II) and Ruthenium (II) metal complexes that
were derived from 5-Fluorouracil were synthesized and characterized by using …

Novel chemotherapeutic agents against multidrug resistant-tuberculosis (MDR-TB) are
urgently needed at this juncture to save the life of TB-infected patients. In this work, we have …

In this study, ethyl 3‐aminothieno [2, 3‐b] pyridine‐2‐carboxylate was taken as a versatile
precursor for the one‐pot three‐component synthesis of related fused pyrimidine hybrids …

A novel series of isatin hybrids 5a-g was designed, synthesized, and characterized
spectroscopically. The synthesized compounds were evaluated for their cytotoxic activity …

Herein, we report the multicomponent synthesis of pyrido [2, 3‐d] pyrimidine derivatives from
6‐aminouracil, aromatic aldehydes, and malononitrile in glycerol as a green solvent under …

Background: Pyrimidine ring is one of the most important heterocyclic scaffolds due to its
biological benefits as antimicrobial agents via acting as competitive suppressors of …

A library of acetamide and hydrazine analogues were generated on the pyrimidine ring
through a multistep reaction starting from 5‐nitro‐pyrimidine‐4, 6‐diol and pyrimidine‐4, 6 …