The Cannabis plant contains numerous components, including cannabinoids and other
active molecules. The phyto-cannabinoid activity is mediated by the endocannabinoid …

Helminths stage a powerful infection that allows the parasite to damage host tissue through
migration and feeding while simultaneously evading the host immune system. This feat is …

The impact of the host immune environment on parasite transcription and fitness is currently
unknown. It is widely held that hookworm infections have an immunomodulatory impact on …

Macrophages are a heterogeneous population of innate immune cells that are often divided
into two major subsets: classically activated, typically pro-inflammatory (M1) macrophages …

Chronic helminth infections (CHIs) can induce immunological tolerance through the
upregulation of regulatory T cells. In coronavirus disease 2019 (COVID‐19), abnormal …

Background Manipulative parasites are thought to liberate molecules in their external
environment, acting as manipulation factors with biological functions implicated in their …

Cannabis has long been used for its medicinal and psychoactive properties. With the
relatively new adoption of formal medicinal cannabis regulations worldwide, the study of …

The endocannabinoid signalling (ECS) system is a complex lipid signalling pathway that
modulates diverse physiological processes in both vertebrate and invertebrate systems. In …

Parasites can exert strong selective pressures on their hosts and influence the evolution of
host immunity. While several studies have examined the genetic basis for parasite …

Macrophages intimately interact with intestinal epithelial cells, but the consequences of
defective macrophage–epithelial cell interactions for protection against enteric pathogens …