Pseudomonas aeruginosa Lifestyle: A Paradigm for Adaptation, Survival, and Persistence

MF Moradali, S Ghods, BHA Rehm - Frontiers in cellular and infection …, 2017 - frontiersin.org
Pseudomonas aeruginosa is an opportunistic pathogen affecting immunocompromised
patients. It is known as the leading cause of morbidity and mortality in cystic fibrosis (CF) …

Pseudomonas aeruginosa Twitching Motility: Type IV Pili in Action

LL Burrows - Annual review of microbiology, 2012 - annualreviews.org
Type IV pili (T4P) are one of the most common forms of bacterial and archaeal surface
structures, involved in adherence, motility, competence for DNA uptake, and pathogenesis …

Architecture of the type IVa pilus machine

YW Chang, L Rettberg, A Treuner-Lange, J Iwasa… - Biophysical …, 2016 - cell.com
Type IV pili are part of a widespread superfamily of bacterial and archaeal cell surface
structures important for biofilm formation, motility, host adhesion, predation, DNA uptake …

A comprehensive guide to pilus biogenesis in Gram-negative bacteria

MK Hospenthal, TRD Costa, G Waksman - Nature reviews microbiology, 2017 - nature.com
Pili are crucial virulence factors for many Gram-negative pathogens. These surface
structures provide bacteria with a link to their external environments by enabling them to …

Type IV pilin proteins: versatile molecular modules

CL Giltner, Y Nguyen, LL Burrows - Microbiology and molecular …, 2012 - Am Soc Microbiol
SUMMARY Type IV pili (T4P) are multifunctional protein fibers produced on the surfaces of a
wide variety of bacteria and archaea. The major subunit of T4P is the type IV pilin, and …

Exceptionally widespread nanomachines composed of type IV pilins: the prokaryotic Swiss Army knives

JL Berry, V Pelicic - FEMS microbiology reviews, 2015 - academic.oup.com
Prokaryotes have engineered sophisticated surface nanomachines that have allowed them
to colonize Earth and thrive even in extreme environments. Filamentous machineries …

A hierarchical cascade of second messengers regulates Pseudomonas aeruginosa surface behaviors

Y Luo, K Zhao, AE Baker, SL Kuchma, KA Coggan… - MBio, 2015 - Am Soc Microbiol
Biofilms are surface-attached multicellular communities. Using single-cell tracking
microscopy, we showed that a pilY1 mutant of Pseudomonas aeruginosa is defective in …

Bacterial flagella hijack type IV pili proteins to control motility

X Liu, S Tachiyama, X Zhou… - Proceedings of the …, 2024 - National Acad Sciences
Bacterial flagella and type IV pili (TFP) are surface appendages that enable motility and
mechanosensing through distinct mechanisms. These structures were previously thought to …

Type IV pili in Gram-positive bacteria

S Melville, L Craig - Microbiology and molecular biology reviews, 2013 - Am Soc Microbiol
SUMMARY Type IV pili (T4P) are surface-exposed fibers that mediate many functions in
bacteria, including locomotion, adherence to host cells, DNA uptake (competence), and …

[HTML][HTML] Type II secretion system: a magic beanstalk or a protein escalator

M Nivaskumar, O Francetic - … et Biophysica Acta (BBA)-Molecular Cell …, 2014 - Elsevier
Type II protein secretion systems (T2SS) are molecular machines that promote specific
transport of folded periplasmic proteins in Gram-negative bacteria, across a dedicated …