Mechanism of action of ribosomally synthesized and post-translationally modified peptides

C Ongpipattanakul, EK Desormeaux… - Chemical …, 2022 - ACS Publications
Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Copper active sites in biology

EI Solomon, DE Heppner, EM Johnston… - Chemical …, 2014 - ACS Publications
On the basis of its generally accessible I/II redox couple and bioavailability, copper plays a
wide variety of roles in nature that mostly involve electron transfer (ET), O 2 binding …

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

PG Arnison, MJ Bibb, G Bierbaum, AA Bowers… - Natural product …, 2013 - pubs.rsc.org
Covering: 1988 to 2012 This review presents recommended nomenclature for the
biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs) …

Methanotrophs and copper

JD Semrau, AA DiSpirito, S Yoon - FEMS microbiology reviews, 2010 - academic.oup.com
Methanotrophs, cells that consume methane (CH4) as their sole source of carbon and
energy, play key roles in the global carbon cycle, including controlling anthropogenic and …

Direct Methane Oxidation by Copper-and Iron-Dependent Methane Monooxygenases

FJ Tucci, AC Rosenzweig - Chemical reviews, 2024 - ACS Publications
Methane is a potent greenhouse gas that contributes significantly to climate change and is
primarily regulated in Nature by methanotrophic bacteria, which consume methane gas as …

The siderophore yersiniabactin binds copper to protect pathogens during infection

KS Chaturvedi, CS Hung, JR Crowley… - Nature chemical …, 2012 - nature.com
Bacterial pathogens secrete chemically diverse iron chelators called siderophores, which
may exert additional distinctive functions in vivo. Among these, uropathogenic Escherichia …

Cu homeostasis in bacteria: the ins and outs

A Andrei, Y Öztürk, B Khalfaoui-Hassani, J Rauch… - Membranes, 2020 - mdpi.com
Copper (Cu) is an essential trace element for all living organisms and used as cofactor in
key enzymes of important biological processes, such as aerobic respiration or superoxide …

Metals and methanotrophy

JD Semrau, AA DiSpirito, W Gu… - Applied and …, 2018 - Am Soc Microbiol
Aerobic methanotrophs have long been known to play a critical role in the global carbon
cycle, being capable of converting methane to biomass and carbon dioxide. Interestingly …

Methanobactin reverses acute liver failure in a rat model of Wilson disease

J Lichtmannegger, C Leitzinger… - The Journal of …, 2016 - Am Soc Clin Investig
In Wilson disease (WD), functional loss of ATPase copper-transporting β (ATP7B) impairs
biliary copper excretion, leading to excessive copper accumulation in the liver and fulminant …

Methanobactin and the link between copper and bacterial methane oxidation

AA DiSpirito, JD Semrau, JC Murrell… - Microbiology and …, 2016 - Am Soc Microbiol
Methanobactins (mbs) are low-molecular-mass (< 1,200 Da) copper-binding peptides, or
chalkophores, produced by many methane-oxidizing bacteria (methanotrophs). These …